Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KXA29577.1Putative adenylyl cyclase CyaB; KEGG: apr:Apre_0779 1.1e-28 adenylate cyclase; K05873 adenylate cyclase, class 2; Psort location: Cytoplasmic, score: 7.50. (177 aa)    
Predicted Functional Partners:
relA
Putative GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
  0.902
nrdD
KEGG: fma:FMG_1178 1.2e-299 anaerobic ribonucleoside triphosphate reductase; K00527 ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 7.50.
     
  0.900
KXA29578.1
Ser/Thr phosphatase family protein; KEGG: cbn:CbC4_0532 2.6e-57 metallophosphoesterase K07099; Psort location: Cytoplasmic, score: 7.50.
       0.818
sbcD
Ser/Thr phosphatase family protein; KEGG: sax:USA300HOU_1836 3.9e-24 sbcD; DNA repair exonuclease; Psort location: Cytoplasmic, score: 7.50.
       0.813
KXA29579.1
Hypothetical protein; KEGG: fnu:FN0522 6.5e-21 exonuclease SbcC K03546; Psort location: CytoplasmicMembrane, score: 8.16.
       0.808
folE
GTP cyclohydrolase I; KEGG: sne:SPN23F_02800 4.0e-70 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50.
     
  0.800
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
  0.800
ppsA
Pyruvate, water dikinase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
       0.619
ycaC
Isochorismatase family protein; KEGG: ddf:DEFDS_0678 2.7e-32 isochorismatase hydrolase; Psort location: Cytoplasmic, score: 7.50.
     
 0.578
lacC
Hypothetical protein; KEGG: cbk:CLL_A3126 8.9e-18 pfkB; 1-phosphofructokinase K00917; Psort location: Cytoplasmic, score: 7.50.
       0.554
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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