STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDSer/Thr phosphatase family protein; KEGG: sax:USA300HOU_1836 3.9e-24 sbcD; DNA repair exonuclease; Psort location: Cytoplasmic, score: 7.50. (339 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.994
KXA29579.1
Hypothetical protein; KEGG: fnu:FN0522 6.5e-21 exonuclease SbcC K03546; Psort location: CytoplasmicMembrane, score: 8.16.
 
 
 0.967
KXA31589.1
DEAD2 domain protein; KEGG: cno:NT01CX_0936 6.3e-175 hypothetical protein; K10844 DNA excision repair protein ERCC-2; Psort location: Cytoplasmic, score: 7.50.
  
 0.889
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.855
KXA29578.1
Ser/Thr phosphatase family protein; KEGG: cbn:CbC4_0532 2.6e-57 metallophosphoesterase K07099; Psort location: Cytoplasmic, score: 7.50.
       0.816
KXA29577.1
Putative adenylyl cyclase CyaB; KEGG: apr:Apre_0779 1.1e-28 adenylate cyclase; K05873 adenylate cyclase, class 2; Psort location: Cytoplasmic, score: 7.50.
       0.815
asnS
asparagine--tRNA ligase; KEGG: ctx:Clo1313_2162 5.5e-176 asparaginyl-tRNA synthetase; K01893 asparaginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00.
  
  0.757
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.713
topB_3
KEGG: apr:Apre_1822 3.7e-296 DNA topoisomerase type IA central domain-containing protein; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97.
  
 0.693
topB_2
KEGG: seq:SZO_12820 7.2e-245 DNA topoisomerase; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97.
  
 0.693
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.