node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adcA_2 | perR | HMPREF3229_01219 | HMPREF3229_01220 | ABC transporter, substrate-binding protein; KEGG: saj:SaurJH9_2430 3.0e-40 ribulose-phosphate 3-epimerase K01783; Psort location: CytoplasmicMembrane, score: 9.68; Belongs to the bacterial solute-binding protein 9 family. | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | 0.672 |
adcA_2 | yusV | HMPREF3229_01219 | HMPREF3229_01218 | ABC transporter, substrate-binding protein; KEGG: saj:SaurJH9_2430 3.0e-40 ribulose-phosphate 3-epimerase K01783; Psort location: CytoplasmicMembrane, score: 9.68; Belongs to the bacterial solute-binding protein 9 family. | KEGG: cth:Cthe_0548 1.4e-44 ABC transporter-like protein; K09817 zinc transport system ATP-binding protein; Psort location: CytoplasmicMembrane, score: 8.78. | 0.981 |
adcA_2 | znuB_2 | HMPREF3229_01219 | HMPREF3229_01217 | ABC transporter, substrate-binding protein; KEGG: saj:SaurJH9_2430 3.0e-40 ribulose-phosphate 3-epimerase K01783; Psort location: CytoplasmicMembrane, score: 9.68; Belongs to the bacterial solute-binding protein 9 family. | ABC 3 transport family protein; KEGG: pfe:PSF113_0030 3.0e-26 znuB; protein ZnuB K09816; Psort location: CytoplasmicMembrane, score: 10.00. | 0.979 |
ahpC | perR | HMPREF3229_01728 | HMPREF3229_01220 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | 0.657 |
ahpC | trxA | HMPREF3229_01728 | HMPREF3229_01891 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Thioredoxin; KEGG: sis:LS215_0050 2.5e-08 thioredoxin K03671; Psort location: Cytoplasmic, score: 7.50. | 0.667 |
birA | perR | HMPREF3229_01815 | HMPREF3229_01220 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | 0.476 |
birA | rpoA | HMPREF3229_01815 | HMPREF3229_01759 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.454 |
birA | rpoD | HMPREF3229_01815 | HMPREF3229_01237 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.402 |
perR | adcA_2 | HMPREF3229_01220 | HMPREF3229_01219 | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | ABC transporter, substrate-binding protein; KEGG: saj:SaurJH9_2430 3.0e-40 ribulose-phosphate 3-epimerase K01783; Psort location: CytoplasmicMembrane, score: 9.68; Belongs to the bacterial solute-binding protein 9 family. | 0.672 |
perR | ahpC | HMPREF3229_01220 | HMPREF3229_01728 | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.657 |
perR | birA | HMPREF3229_01220 | HMPREF3229_01815 | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.476 |
perR | rpoA | HMPREF3229_01220 | HMPREF3229_01759 | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.680 |
perR | rpoB | HMPREF3229_01220 | HMPREF3229_00353 | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.469 |
perR | rpoD | HMPREF3229_01220 | HMPREF3229_01237 | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.620 |
perR | rpoZ | HMPREF3229_01220 | HMPREF3229_00947 | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.469 |
perR | trxA | HMPREF3229_01220 | HMPREF3229_01891 | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | Thioredoxin; KEGG: sis:LS215_0050 2.5e-08 thioredoxin K03671; Psort location: Cytoplasmic, score: 7.50. | 0.538 |
perR | yusV | HMPREF3229_01220 | HMPREF3229_01218 | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | KEGG: cth:Cthe_0548 1.4e-44 ABC transporter-like protein; K09817 zinc transport system ATP-binding protein; Psort location: CytoplasmicMembrane, score: 8.78. | 0.759 |
perR | znuB_2 | HMPREF3229_01220 | HMPREF3229_01217 | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | ABC 3 transport family protein; KEGG: pfe:PSF113_0030 3.0e-26 znuB; protein ZnuB K09816; Psort location: CytoplasmicMembrane, score: 10.00. | 0.745 |
rpoA | birA | HMPREF3229_01759 | HMPREF3229_01815 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.454 |
rpoA | perR | HMPREF3229_01759 | HMPREF3229_01220 | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcriptional regulator, Fur family; KEGG: mct:MCR_0333 5.8e-14 fur; ferric uptake regulation protein Fur K03711; Psort location: Cytoplasmic, score: 9.97; Belongs to the Fur family. | 0.680 |