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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaX_2DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (577 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.972
KXA29647.1
KEGG: amt:Amet_3057 1.3e-41 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta.
   
 0.972
dnaE
KEGG: txy:Thexy_0632 0. DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.969
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
 0.964
KXA29600.1
DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.908
KXA28921.1
BRCA1 protein; KEGG: sri:SELR_11040 5.1e-70 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.770
ssb
KEGG: shn:Shewana3_3590 3.1e-15 single-strand binding protein K03111; Psort location: Cytoplasmic, score: 9.67.
   
 
 0.687
KXA28940.1
KEGG: shn:Shewana3_3590 2.0e-11 single-strand binding protein K03111; Psort location: Cytoplasmic, score: 9.67.
   
 
 0.687
KXA31238.1
Hypothetical protein; KEGG: bbu:BB_0259 0.0045 transglycosylase SLT domain protein; K08309 soluble lytic murein transglycosylase.
   
 
 0.666
dnaC
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
 
 
 0.641
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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