STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoDRNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (362 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 0.993
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.946
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.928
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.921
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.904
KXA30411.1
CarD-like protein; KEGG: apb:SAR116_1070 1.5e-15 transcriptional regulator K07736; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.880
KXA31896.1
Cyclic nucleotide-binding domain protein; KEGG: fma:FMG_1494 0.00029 pyruvate-formate-lyase-activating enzyme; K04069 pyruvate formate lyase activating enzyme; Psort location: Cytoplasmic, score: 7.50.
    
 
 0.874
ccpN
Putative transcriptional repressor CcpN; KEGG: ppo:PPM_2177 1.9e-38 yqzB; inosine-5'-monophosphate dehydrogenase IMP dehydrogenase; IMPDH; IMPD; Psort location: Cytoplasmic, score: 7.50.
     
 0.873
trmK
Hypothetical protein; KEGG: twi:Thewi_1680 2.6e-34 hypothetical protein; K06967 tRNA (adenine22-N1)-methyltransferase; Psort location: Cytoplasmic, score: 7.50.
 
     0.840
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
 
 
 
 0.838
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.