Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dgtPutative dGTPase; KEGG: eel:EUBELI_00675 3.8e-104 deoxyguanosinetriphosphate triphosphohydrolase-like protein; K01129 dGTPase; Psort location: Cytoplasmic, score: 7.50; Belongs to the dGTPase family. Type 2 subfamily. (337 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
    
 0.912
surE_3
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.910
punA
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
  0.904
nrdD
KEGG: fma:FMG_1178 1.2e-299 anaerobic ribonucleoside triphosphate reductase; K00527 ribonucleoside-triphosphate reductase; Psort location: Cytoplasmic, score: 7.50.
    
  0.902
ccpN
Putative transcriptional repressor CcpN; KEGG: ppo:PPM_2177 1.9e-38 yqzB; inosine-5'-monophosphate dehydrogenase IMP dehydrogenase; IMPDH; IMPD; Psort location: Cytoplasmic, score: 7.50.
     
 0.834
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
     
 0.823
era
Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
     
 0.811
KXA29610.1
Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 7.4e-14 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 7.50.
       0.809
trmK
Hypothetical protein; KEGG: twi:Thewi_1680 2.6e-34 hypothetical protein; K06967 tRNA (adenine22-N1)-methyltransferase; Psort location: Cytoplasmic, score: 7.50.
       0.809
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
       0.809
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.