Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXA29633.1Histidine triad domain protein; KEGG: cbj:H04402_03042 2.0e-36 bis(5'-nucleosyl)-tetraphosphatase; Psort location: Cytoplasmic, score: 7.50. (112 aa)    
Predicted Functional Partners:
miaB_1
tRNA methylthiotransferase YqeV; KEGG: cdf:CD2448 8.8e-114 radical SAM superfamily protein; K08070 2-alkenal reductase; Psort location: Cytoplasmic, score: 7.50.
  
   0.847
lysS
lysine--tRNA ligase; KEGG: fma:FMG_0987 2.5e-251 lysyl-tRNA synthetase class II; K04567 lysyl-tRNA synthetase, class II; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.813
udk
Uridine kinase; KEGG: aoe:Clos_1655 5.8e-69 uridine kinase; K00876 uridine kinase; Psort location: Cytoplasmic, score: 9.97.
   
 0.791
cobB
Putative NAD-dependent deacetylase; KEGG: ttm:Tthe_1994 1.2e-70 silent information regulator protein Sir2; K12410 NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 7.50.
  
 
  0.775
KXA29634.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.773
tlyA
Ribosomal RNA large subunit methyltransferase J; KEGG: aoe:Clos_1606 6.1e-74 hemolysin A; K06442 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase; Psort location: Cytoplasmic, score: 7.50.
      0.758
rsmE
RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
     
 0.748
prmA
Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
     
 0.741
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.640
dnaJ_2
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 
 0.603
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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