STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXA29647.1KEGG: amt:Amet_3057 1.3e-41 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta. (336 aa)    
Predicted Functional Partners:
dnaX_1
Hypothetical protein; KEGG: aoe:Clos_0062 1.8e-42 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.980
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.977
dnaX_2
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.972
dnaE
KEGG: txy:Thexy_0632 0. DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.960
KXA29648.1
KEGG: apb:SAR116_0501 2.8e-09 DNA uptake protein ComEC K02238; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.889
KXA29649.1
Hypothetical protein; KEGG: ddi:DDB_G0274493 8.1e-14 lig1; DNA ligase I; K10747 DNA ligase 1; Psort location: Cytoplasmic, score: 7.50.
 
     0.693
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
     
 0.622
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.607
KXA28921.1
BRCA1 protein; KEGG: sri:SELR_11040 5.1e-70 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97.
    
 
 0.581
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.480
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.