| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA29660.1 | glmS | HMPREF3229_01286 | HMPREF3229_01285 | Hypothetical protein; KEGG: hpa:HPAG1_1423 1.9e-40 hemolysin domain-containing protein K00088; Psort location: CytoplasmicMembrane, score: 9.99. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.605 |
| KXA29660.1 | guaA | HMPREF3229_01286 | HMPREF3229_00210 | Hypothetical protein; KEGG: hpa:HPAG1_1423 1.9e-40 hemolysin domain-containing protein K00088; Psort location: CytoplasmicMembrane, score: 9.99. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.503 |
| carB | glmS | HMPREF3229_01336 | HMPREF3229_01285 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.935 |
| carB | glsA_2 | HMPREF3229_01336 | HMPREF3229_01485 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | KEGG: tva:TVAG_134820 8.2e-118 Glutaminase family protein; K01425 glutaminase; Psort location: Cytoplasmic, score: 7.50; Belongs to the glutaminase family. | 0.900 |
| carB | gltD | HMPREF3229_01336 | HMPREF3229_01902 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | Glutamate synthase; KEGG: clj:CLJU_c37240 2.7e-261 glutamate synthase K00266; Psort location: Cytoplasmic, score: 9.97. | 0.981 |
| carB | guaA | HMPREF3229_01336 | HMPREF3229_00210 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.802 |
| carB | metG_1 | HMPREF3229_01336 | HMPREF3229_00579 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.453 |
| carB | purL | HMPREF3229_01336 | HMPREF3229_01479 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | KEGG: apr:Apre_1107 0. phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 9.97. | 0.633 |
| echA8_2 | glmS | HMPREF3229_00593 | HMPREF3229_01285 | enoyl-CoA hydratase/isomerase family protein; KEGG: oih:OB0817 5.0e-47 3-hydroxyisobutyryl-CoA hydrolase; Psort location: Cytoplasmic, score: 7.50. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.681 |
| echA8_2 | gltD | HMPREF3229_00593 | HMPREF3229_01902 | enoyl-CoA hydratase/isomerase family protein; KEGG: oih:OB0817 5.0e-47 3-hydroxyisobutyryl-CoA hydrolase; Psort location: Cytoplasmic, score: 7.50. | Glutamate synthase; KEGG: clj:CLJU_c37240 2.7e-261 glutamate synthase K00266; Psort location: Cytoplasmic, score: 9.97. | 0.460 |
| glmM | glmS | HMPREF3229_00416 | HMPREF3229_01285 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.957 |
| glmM | glmU | HMPREF3229_00416 | HMPREF3229_00298 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.994 |
| glmM | guaA | HMPREF3229_00416 | HMPREF3229_00210 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.429 |
| glmS | KXA29660.1 | HMPREF3229_01285 | HMPREF3229_01286 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Hypothetical protein; KEGG: hpa:HPAG1_1423 1.9e-40 hemolysin domain-containing protein K00088; Psort location: CytoplasmicMembrane, score: 9.99. | 0.605 |
| glmS | carB | HMPREF3229_01285 | HMPREF3229_01336 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | 0.935 |
| glmS | echA8_2 | HMPREF3229_01285 | HMPREF3229_00593 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | enoyl-CoA hydratase/isomerase family protein; KEGG: oih:OB0817 5.0e-47 3-hydroxyisobutyryl-CoA hydrolase; Psort location: Cytoplasmic, score: 7.50. | 0.681 |
| glmS | glmM | HMPREF3229_01285 | HMPREF3229_00416 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.957 |
| glmS | glmU | HMPREF3229_01285 | HMPREF3229_00298 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.914 |
| glmS | glsA_2 | HMPREF3229_01285 | HMPREF3229_01485 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | KEGG: tva:TVAG_134820 8.2e-118 Glutaminase family protein; K01425 glutaminase; Psort location: Cytoplasmic, score: 7.50; Belongs to the glutaminase family. | 0.903 |
| glmS | gltD | HMPREF3229_01285 | HMPREF3229_01902 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glutamate synthase; KEGG: clj:CLJU_c37240 2.7e-261 glutamate synthase K00266; Psort location: Cytoplasmic, score: 9.97. | 0.924 |