STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIThiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (393 aa)    
Predicted Functional Partners:
iscS_2
Putative cysteine desulfurase; KEGG: toc:Toce_1465 7.4e-85 class V aminotransferase; K04487 cysteine desulfurase; Psort location: Cytoplasmic, score: 9.97.
 
 0.992
rsmB
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.833
KXA29385.1
LemA family protein.
       0.797
KXA29384.1
Hypothetical protein; KEGG: xfa:XF0818 3.8e-09 endo-1,4-beta-glucanase; K01179 endoglucanase; Psort location: CytoplasmicMembrane, score: 9.93.
       0.795
nifS
KEGG: clb:Clo1100_2273 4.1e-100 cysteine desulfurase NifS; K04487 cysteine desulfurase; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.658
KXA28857.1
Aminotransferase, class V; KEGG: apr:Apre_0365 6.5e-70 cysteine desulfurase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.615
KXA29388.1
Hypothetical protein; KEGG: fnu:FN1237 0.0060 choline kinase; Psort location: Cytoplasmic, score: 7.50.
       0.571
rny
YmdA/YtgF family protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
 
   
 0.504
miaB_1
tRNA methylthiotransferase YqeV; KEGG: cdf:CD2448 8.8e-114 radical SAM superfamily protein; K08070 2-alkenal reductase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.484
queA
S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
  
  
 0.469
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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