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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metQ_2Putative D-methionine-binding lipoprotein MetQ; KEGG: pfe:PSF113_0025 1.4e-58 nlpA; protein NlpA K02073; Psort location: CytoplasmicMembrane, score: 9.68; Belongs to the nlpA lipoprotein family. (282 aa)    
Predicted Functional Partners:
metN_1
ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 0.999
metP
KEGG: pfe:PSF113_0026 1.1e-44 D-Methionine ABC transporter permease protein K02072; Psort location: CytoplasmicMembrane, score: 10.00.
 
 0.999
metQ_1
Lipoprotein, YaeC family; KEGG: pfe:PSF113_0025 4.1e-61 nlpA; protein NlpA K02073; Psort location: CytoplasmicMembrane, score: 9.68; Belongs to the nlpA lipoprotein family.
 
    
0.658
mdeA
KEGG: bfr:BF3545 2.3e-168 O-acetylhomoserine (thiol)-lyase; K01740 O-acetylhomoserine (thiol)-lyase; Psort location: Cytoplasmic, score: 9.67.
  
    0.612
KXA29160.1
Hypothetical protein; Psort location: Extracellular, score: 8.91.
       0.553
htrA
Trypsin; KEGG: aoe:Clos_2777 7.6e-76 2-alkenal reductase.
       0.511
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
  
 0.457
metK_2
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.430
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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