Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rpiBRibose-5-phosphate isomerase B; KEGG: cbn:CbC4_2276 1.8e-42 rpiB; ribose 5-phosphate isomerase B; K01808 ribose 5-phosphate isomerase B; Psort location: Cytoplasmic, score: 7.50. (143 aa)    
Predicted Functional Partners:
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
    0.980
rpe
KEGG: rho:RHOM_09980 2.9e-60 ribulose-phosphate 3-epimerase; K01783 ribulose-phosphate 3-epimerase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.943
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.934
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.929
pgcA
KEGG: taf:THA_1027 9.4e-133 phosphoglucomutase/phosphomannomutase family protein; K01840 phosphomannomutase; Psort location: Cytoplasmic, score: 7.50.
    
 0.908
deoC1
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
 0.827
mraY_1
Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00.
  
    0.810
rimN
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
       0.805
mnaA
UDP-N-acetylglucosamine 2-epimerase; KEGG: cst:CLOST_2125 6.7e-116 rffE; UDP-N-acetyl glucosamine-2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
       0.800
rbgA
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
      0.689
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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