| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA29704.1 | mraY_1 | HMPREF3229_01330 | HMPREF3229_01418 | Polysaccharide pyruvyl transferase CsaB; KEGG: csc:Csac_1349 1.5e-61 glycosyl transferase family protein K05946. | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | 0.653 |
| KXA29704.1 | tagA | HMPREF3229_01330 | HMPREF3229_00620 | Polysaccharide pyruvyl transferase CsaB; KEGG: csc:Csac_1349 1.5e-61 glycosyl transferase family protein K05946. | Glycosyltransferase, WecB/TagA/CpsF family; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. | 0.938 |
| mnaA | mraY_1 | HMPREF3229_01419 | HMPREF3229_01418 | UDP-N-acetylglucosamine 2-epimerase; KEGG: cst:CLOST_2125 6.7e-116 rffE; UDP-N-acetyl glucosamine-2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | 0.987 |
| mnaA | rimN | HMPREF3229_01419 | HMPREF3229_01415 | UDP-N-acetylglucosamine 2-epimerase; KEGG: cst:CLOST_2125 6.7e-116 rffE; UDP-N-acetyl glucosamine-2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.790 |
| mnaA | rpiB | HMPREF3229_01419 | HMPREF3229_01416 | UDP-N-acetylglucosamine 2-epimerase; KEGG: cst:CLOST_2125 6.7e-116 rffE; UDP-N-acetyl glucosamine-2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | Ribose-5-phosphate isomerase B; KEGG: cbn:CbC4_2276 1.8e-42 rpiB; ribose 5-phosphate isomerase B; K01808 ribose 5-phosphate isomerase B; Psort location: Cytoplasmic, score: 7.50. | 0.785 |
| mnaA | upp | HMPREF3229_01419 | HMPREF3229_01417 | UDP-N-acetylglucosamine 2-epimerase; KEGG: cst:CLOST_2125 6.7e-116 rffE; UDP-N-acetyl glucosamine-2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.794 |
| mraY_1 | KXA29704.1 | HMPREF3229_01418 | HMPREF3229_01330 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | Polysaccharide pyruvyl transferase CsaB; KEGG: csc:Csac_1349 1.5e-61 glycosyl transferase family protein K05946. | 0.653 |
| mraY_1 | mnaA | HMPREF3229_01418 | HMPREF3229_01419 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | UDP-N-acetylglucosamine 2-epimerase; KEGG: cst:CLOST_2125 6.7e-116 rffE; UDP-N-acetyl glucosamine-2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.987 |
| mraY_1 | murD | HMPREF3229_01418 | HMPREF3229_00935 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.784 |
| mraY_1 | murE | HMPREF3229_01418 | HMPREF3229_00922 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: faa:HMPREF0389_00596 1.8e-122 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 9.97. | 0.689 |
| mraY_1 | murF | HMPREF3229_01418 | HMPREF3229_00256 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; KEGG: tte:TTE2546 4.7e-99 MurF; UDP-N-acetylmuramyl pentapeptide synthase; K01929 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Psort location: Cytoplasmic, score: 9.95. | 0.789 |
| mraY_1 | murG | HMPREF3229_01418 | HMPREF3229_00937 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.691 |
| mraY_1 | rimN | HMPREF3229_01418 | HMPREF3229_01415 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.780 |
| mraY_1 | rpiB | HMPREF3229_01418 | HMPREF3229_01416 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | Ribose-5-phosphate isomerase B; KEGG: cbn:CbC4_2276 1.8e-42 rpiB; ribose 5-phosphate isomerase B; K01808 ribose 5-phosphate isomerase B; Psort location: Cytoplasmic, score: 7.50. | 0.795 |
| mraY_1 | tagA | HMPREF3229_01418 | HMPREF3229_00620 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | Glycosyltransferase, WecB/TagA/CpsF family; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. | 0.799 |
| mraY_1 | upp | HMPREF3229_01418 | HMPREF3229_01417 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.796 |
| murD | mraY_1 | HMPREF3229_00935 | HMPREF3229_01418 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | 0.784 |
| murD | murE | HMPREF3229_00935 | HMPREF3229_00922 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: faa:HMPREF0389_00596 1.8e-122 UDP-N-acetylmuramyl tripeptide synthetase; K01928 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Psort location: Cytoplasmic, score: 9.97. | 0.943 |
| murD | murF | HMPREF3229_00935 | HMPREF3229_00256 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; KEGG: tte:TTE2546 4.7e-99 MurF; UDP-N-acetylmuramyl pentapeptide synthase; K01929 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Psort location: Cytoplasmic, score: 9.95. | 0.842 |
| murD | murG | HMPREF3229_00935 | HMPREF3229_00937 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.993 |