Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mnaAUDP-N-acetylglucosamine 2-epimerase; KEGG: cst:CLOST_2125 6.7e-116 rffE; UDP-N-acetyl glucosamine-2-epimerase K01791; Psort location: Cytoplasmic, score: 9.97; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (367 aa)    
Predicted Functional Partners:
mraY_1
Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.990
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
    
 0.926
murAA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
 
 0.917
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
 0.846
rimN
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
  
    0.804
rpiB
Ribose-5-phosphate isomerase B; KEGG: cbn:CbC4_2276 1.8e-42 rpiB; ribose 5-phosphate isomerase B; K01808 ribose 5-phosphate isomerase B; Psort location: Cytoplasmic, score: 7.50.
       0.800
ltaS1
Arylsulfatase; KEGG: bmd:BMD_0202 3.1e-47 sulfatase; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.605
thlA
KEGG: apr:Apre_1351 5.6e-151 acetyl-CoA acetyltransferase; K00626 acetyl-CoA C-acetyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the thiolase-like superfamily. Thiolase family.
  
    0.568
abgB_1
Amidohydrolase; KEGG: bcl:ABC1615 6.6e-77 N-acyl-L-amino acid amidohydrolase K01436; Psort location: Cytoplasmic, score: 7.50; Belongs to the peptidase M20A family.
       0.566
mraY_2
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
  
 0.497
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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