Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pyrBKEGG: awo:Awo_c16150 1.1e-104 pyrB; aspartate carbamoyltransferase catalytic subunit PyrB K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (307 aa)    
Predicted Functional Partners:
pyrC
Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 0.999
carB
KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family.
 
 0.999
pyrI
Aspartate carbamoyltransferase regulatory chain, allosteric domain protein; KEGG: awo:Awo_c16160 1.5e-40 pyrI; aspartate carbamoyltransferase regulatory subunit PyrI K00610.
 
 0.999
pyrDB
Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate.
 
  
 0.988
pyrK
KEGG: ctc:CTC00929 2.6e-57 dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.987
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.932
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.930
KXA29192.1
Putative aspartate transaminase; KEGG: cex:CSE_13400 5.1e-86 aspartate aminotransferase; Psort location: Cytoplasmic, score: 7.50.
    
 0.924
nadB
FAD binding domain protein; KEGG: fnu:FN0009 2.4e-102 L-aspartate oxidase K00278; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.907
aspC
Aminotransferase, class I/II; KEGG: amt:Amet_2618 4.2e-107 aspartate aminotransferase K00812; Psort location: Cytoplasmic, score: 7.50.
    
 0.905
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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