| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| asnA | pyrB | HMPREF3229_00906 | HMPREF3229_01431 | Aspartate--ammonia ligase; KEGG: fnu:FN0776 8.9e-105 asparagine synthetase AsnA K01914; Psort location: Cytoplasmic, score: 10.00. | KEGG: awo:Awo_c16150 1.1e-104 pyrB; aspartate carbamoyltransferase catalytic subunit PyrB K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.901 |
| asnA | pyrI | HMPREF3229_00906 | HMPREF3229_01432 | Aspartate--ammonia ligase; KEGG: fnu:FN0776 8.9e-105 asparagine synthetase AsnA K01914; Psort location: Cytoplasmic, score: 10.00. | Aspartate carbamoyltransferase regulatory chain, allosteric domain protein; KEGG: awo:Awo_c16160 1.5e-40 pyrI; aspartate carbamoyltransferase regulatory subunit PyrI K00610. | 0.900 |
| asnA | thrA | HMPREF3229_00906 | HMPREF3229_00218 | Aspartate--ammonia ligase; KEGG: fnu:FN0776 8.9e-105 asparagine synthetase AsnA K01914; Psort location: Cytoplasmic, score: 10.00. | Aspartate kinase; KEGG: fma:FMG_0317 1.9e-196 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family. | 0.800 |
| carB | pyrB | HMPREF3229_01336 | HMPREF3229_01431 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | KEGG: awo:Awo_c16150 1.1e-104 pyrB; aspartate carbamoyltransferase catalytic subunit PyrB K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carB | pyrC | HMPREF3229_01336 | HMPREF3229_00850 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.992 |
| carB | pyrDB | HMPREF3229_01336 | HMPREF3229_01434 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | 0.899 |
| carB | pyrF | HMPREF3229_01336 | HMPREF3229_00768 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.869 |
| carB | pyrI | HMPREF3229_01336 | HMPREF3229_01432 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | Aspartate carbamoyltransferase regulatory chain, allosteric domain protein; KEGG: awo:Awo_c16160 1.5e-40 pyrI; aspartate carbamoyltransferase regulatory subunit PyrI K00610. | 0.963 |
| carB | pyrK | HMPREF3229_01336 | HMPREF3229_01433 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | KEGG: ctc:CTC00929 2.6e-57 dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.97. | 0.873 |
| carB | upp | HMPREF3229_01336 | HMPREF3229_01417 | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.504 |
| gmk_1 | pyrB | HMPREF3229_01430 | HMPREF3229_01431 | Putative guanylate kinase; KEGG: sul:SYO3AOP1_0874 5.9e-21 gmk; guanylate kinase K00942; Psort location: Cytoplasmic, score: 9.97. | KEGG: awo:Awo_c16150 1.1e-104 pyrB; aspartate carbamoyltransferase catalytic subunit PyrB K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.638 |
| gmk_1 | pyrDB | HMPREF3229_01430 | HMPREF3229_01434 | Putative guanylate kinase; KEGG: sul:SYO3AOP1_0874 5.9e-21 gmk; guanylate kinase K00942; Psort location: Cytoplasmic, score: 9.97. | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | 0.638 |
| gmk_1 | pyrI | HMPREF3229_01430 | HMPREF3229_01432 | Putative guanylate kinase; KEGG: sul:SYO3AOP1_0874 5.9e-21 gmk; guanylate kinase K00942; Psort location: Cytoplasmic, score: 9.97. | Aspartate carbamoyltransferase regulatory chain, allosteric domain protein; KEGG: awo:Awo_c16160 1.5e-40 pyrI; aspartate carbamoyltransferase regulatory subunit PyrI K00610. | 0.544 |
| gmk_1 | pyrK | HMPREF3229_01430 | HMPREF3229_01433 | Putative guanylate kinase; KEGG: sul:SYO3AOP1_0874 5.9e-21 gmk; guanylate kinase K00942; Psort location: Cytoplasmic, score: 9.97. | KEGG: ctc:CTC00929 2.6e-57 dihydroorotate dehydrogenase electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.97. | 0.583 |
| pyrB | asnA | HMPREF3229_01431 | HMPREF3229_00906 | KEGG: awo:Awo_c16150 1.1e-104 pyrB; aspartate carbamoyltransferase catalytic subunit PyrB K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Aspartate--ammonia ligase; KEGG: fnu:FN0776 8.9e-105 asparagine synthetase AsnA K01914; Psort location: Cytoplasmic, score: 10.00. | 0.901 |
| pyrB | carB | HMPREF3229_01431 | HMPREF3229_01336 | KEGG: awo:Awo_c16150 1.1e-104 pyrB; aspartate carbamoyltransferase catalytic subunit PyrB K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | KEGG: cdg:CDBI1_17580 0. carB; carbamoyl phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97; Belongs to the CarB family. | 0.999 |
| pyrB | gmk_1 | HMPREF3229_01431 | HMPREF3229_01430 | KEGG: awo:Awo_c16150 1.1e-104 pyrB; aspartate carbamoyltransferase catalytic subunit PyrB K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Putative guanylate kinase; KEGG: sul:SYO3AOP1_0874 5.9e-21 gmk; guanylate kinase K00942; Psort location: Cytoplasmic, score: 9.97. | 0.638 |
| pyrB | pyrC | HMPREF3229_01431 | HMPREF3229_00850 | KEGG: awo:Awo_c16150 1.1e-104 pyrB; aspartate carbamoyltransferase catalytic subunit PyrB K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
| pyrB | pyrDB | HMPREF3229_01431 | HMPREF3229_01434 | KEGG: awo:Awo_c16150 1.1e-104 pyrB; aspartate carbamoyltransferase catalytic subunit PyrB K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate. | 0.979 |
| pyrB | pyrF | HMPREF3229_01431 | HMPREF3229_00768 | KEGG: awo:Awo_c16150 1.1e-104 pyrB; aspartate carbamoyltransferase catalytic subunit PyrB K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.869 |