STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purPPutative permease; KEGG: bcz:BCZK0244 3.7e-99 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. (441 aa)    
Predicted Functional Partners:
purL
KEGG: apr:Apre_1107 0. phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.848
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.575
ygfU
Putative permease; KEGG: apb:SAR116_1372 7.0e-57 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.565
KXA29207.1
Hypothetical protein.
       0.558
purD
KEGG: cdc:CD196_0234 3.3e-114 purD; phosphoribosylamine--glycine ligase; K01945 phosphoribosylamine--glycine ligase; Psort location: Cytoplasmic, score: 7.50; Belongs to the GARS family.
  
  
 0.530
purM
KEGG: awo:Awo_c16370 5.9e-108 purM; phosphoribosylformylglycinamidine cyclo-ligase PurM K01933; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.525
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
  
 0.521
purC
KEGG: faa:HMPREF0389_00399 6.9e-66 phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.520
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.516
purH
KEGG: tmt:Tmath_0637 1.1e-138 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.503
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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