| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA28884.1 | dnaC | HMPREF3229_01516 | HMPREF3229_01513 | Hypothetical protein; KEGG: clp:CPK_ORF00408 0.0067 putative CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.800 |
| KXA28884.1 | nrnA_1 | HMPREF3229_01516 | HMPREF3229_01515 | Hypothetical protein; KEGG: clp:CPK_ORF00408 0.0067 putative CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.861 |
| KXA28884.1 | ramA | HMPREF3229_01516 | HMPREF3229_01511 | Hypothetical protein; KEGG: clp:CPK_ORF00408 0.0067 putative CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00. | Hydrolase, carbon-nitrogen family; KEGG: rno:288174 1.9e-47 Nit2, MGC124762, RGD1310494; nitrilase family, member 2 K13566; Psort location: Cytoplasmic, score: 7.50. | 0.682 |
| KXA28884.1 | rplI | HMPREF3229_01516 | HMPREF3229_01514 | Hypothetical protein; KEGG: clp:CPK_ORF00408 0.0067 putative CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.923 |
| KXA28884.1 | uppP | HMPREF3229_01516 | HMPREF3229_01512 | Hypothetical protein; KEGG: clp:CPK_ORF00408 0.0067 putative CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.683 |
| KXA29005.1 | msrAB | HMPREF3229_01477 | HMPREF3229_00757 | Hypothetical protein; KEGG: mpx:MPD5_0800 2.3e-161 hypothetical protein; K14205 phosphatidylglycerol lysyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.638 |
| KXA29005.1 | uppP | HMPREF3229_01477 | HMPREF3229_01512 | Hypothetical protein; KEGG: mpx:MPD5_0800 2.3e-161 hypothetical protein; K14205 phosphatidylglycerol lysyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.447 |
| dnaC | KXA28884.1 | HMPREF3229_01513 | HMPREF3229_01516 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein; KEGG: clp:CPK_ORF00408 0.0067 putative CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.800 |
| dnaC | nrnA_1 | HMPREF3229_01513 | HMPREF3229_01515 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | 0.839 |
| dnaC | ramA | HMPREF3229_01513 | HMPREF3229_01511 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Hydrolase, carbon-nitrogen family; KEGG: rno:288174 1.9e-47 Nit2, MGC124762, RGD1310494; nitrilase family, member 2 K13566; Psort location: Cytoplasmic, score: 7.50. | 0.690 |
| dnaC | rplI | HMPREF3229_01513 | HMPREF3229_01514 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Ribosomal protein L9; Binds to the 23S rRNA. | 0.882 |
| dnaC | uppP | HMPREF3229_01513 | HMPREF3229_01512 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.696 |
| mraY_1 | uppP | HMPREF3229_01418 | HMPREF3229_01512 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.927 |
| mraY_1 | uppS | HMPREF3229_01418 | HMPREF3229_01139 | Glycosyltransferase, group 4 family; KEGG: cst:CLOST_2126 2.2e-85 tagO; tago K13685; Psort location: CytoplasmicMembrane, score: 10.00. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.479 |
| mraY_2 | uppP | HMPREF3229_00934 | HMPREF3229_01512 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.926 |
| mraY_2 | uppS | HMPREF3229_00934 | HMPREF3229_01139 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.564 |
| msrAB | KXA29005.1 | HMPREF3229_00757 | HMPREF3229_01477 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Hypothetical protein; KEGG: mpx:MPD5_0800 2.3e-161 hypothetical protein; K14205 phosphatidylglycerol lysyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.638 |
| msrAB | uppP | HMPREF3229_00757 | HMPREF3229_01512 | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.448 |
| nrnA_1 | KXA28884.1 | HMPREF3229_01515 | HMPREF3229_01516 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Hypothetical protein; KEGG: clp:CPK_ORF00408 0.0067 putative CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.861 |
| nrnA_1 | dnaC | HMPREF3229_01515 | HMPREF3229_01513 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.839 |
