STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaCReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (456 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 0.982
dnaA
Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 
 0.919
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
  
  
 0.871
dnaI_1
Putative DNA replication protein DnaC; KEGG: aae:aq_2053 0.00047 recG; ATP-dependent DNA helicase RecG; K03655 ATP-dependent DNA helicase RecG; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.847
nrnA_1
DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
  
 0.844
KXA31499.1
Hypothetical protein.
  
 
 0.821
dnaI_3
Replication initiator protein DnaA; KEGG: pfe:PSF113_0001 0.00065 dnaA; ATPase DnaA K02313; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.821
dnaI_2
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.821
KXA28884.1
Hypothetical protein; KEGG: clp:CPK_ORF00408 0.0067 putative CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.787
uppP
Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
       0.695
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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