STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXA28913.1CRISPR-associated endonuclease Cas3-HD; KEGG: rcp:RCAP_rcc01300 7.7e-42 Cas3 family CRISPR-associated helicase K07012. (859 aa)    
Predicted Functional Partners:
cas1
CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.891
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.891
KXA28917.1
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
  
 0.890
KXA28914.1
CRISPR-associated protein Cas5, Dvulg subtype.
 
   
 0.883
KXA28916.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.881
KXA28915.1
CRISPR-associated protein, Csd1 family; KEGG: fnu:FN0522 2.5e-05 exonuclease SbcC K03546.
 
   
 0.841
ghrB
KEGG: sax:USA300HOU_1857 1.1e-40 D-3-phosphoglycerate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.660
KXA28911.1
Tetratricopeptide repeat protein; Psort location: Cytoplasmic, score: 7.50.
       0.454
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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