| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA28623.1 | clpP | HMPREF3229_01619 | HMPREF3229_01621 | Hypothetical protein; KEGG: scp:HMPREF0833_10874 2.9e-19 seryl-tRNA synthetase family protein; Psort location: Cytoplasmic, score: 7.50. | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.620 |
| KXA28623.1 | clpX | HMPREF3229_01619 | HMPREF3229_01622 | Hypothetical protein; KEGG: scp:HMPREF0833_10874 2.9e-19 seryl-tRNA synthetase family protein; Psort location: Cytoplasmic, score: 7.50. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.616 |
| KXA28623.1 | engB | HMPREF3229_01619 | HMPREF3229_01624 | Hypothetical protein; KEGG: scp:HMPREF0833_10874 2.9e-19 seryl-tRNA synthetase family protein; Psort location: Cytoplasmic, score: 7.50. | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.505 |
| KXA28623.1 | lon1 | HMPREF3229_01619 | HMPREF3229_01623 | Hypothetical protein; KEGG: scp:HMPREF0833_10874 2.9e-19 seryl-tRNA synthetase family protein; Psort location: Cytoplasmic, score: 7.50. | Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.505 |
| KXA28623.1 | tig | HMPREF3229_01619 | HMPREF3229_01620 | Hypothetical protein; KEGG: scp:HMPREF0833_10874 2.9e-19 seryl-tRNA synthetase family protein; Psort location: Cytoplasmic, score: 7.50. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.656 |
| KXA28955.1 | clpX | HMPREF3229_01587 | HMPREF3229_01622 | Endopeptidase Clp; KEGG: bcr:BCAH187_A4003 1.6e-43 Clp protease. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.983 |
| KXA28955.1 | lon1 | HMPREF3229_01587 | HMPREF3229_01623 | Endopeptidase Clp; KEGG: bcr:BCAH187_A4003 1.6e-43 Clp protease. | Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.643 |
| KXA28955.1 | msrAB | HMPREF3229_01587 | HMPREF3229_00757 | Endopeptidase Clp; KEGG: bcr:BCAH187_A4003 1.6e-43 Clp protease. | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.408 |
| KXA28955.1 | tig | HMPREF3229_01587 | HMPREF3229_01620 | Endopeptidase Clp; KEGG: bcr:BCAH187_A4003 1.6e-43 Clp protease. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.424 |
| clpP | KXA28623.1 | HMPREF3229_01621 | HMPREF3229_01619 | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Hypothetical protein; KEGG: scp:HMPREF0833_10874 2.9e-19 seryl-tRNA synthetase family protein; Psort location: Cytoplasmic, score: 7.50. | 0.620 |
| clpP | clpX | HMPREF3229_01621 | HMPREF3229_01622 | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.998 |
| clpP | engB | HMPREF3229_01621 | HMPREF3229_01624 | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.695 |
| clpP | lon1 | HMPREF3229_01621 | HMPREF3229_01623 | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.863 |
| clpP | msrAB | HMPREF3229_01621 | HMPREF3229_00757 | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.408 |
| clpP | tig | HMPREF3229_01621 | HMPREF3229_01620 | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.901 |
| clpX | KXA28623.1 | HMPREF3229_01622 | HMPREF3229_01619 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Hypothetical protein; KEGG: scp:HMPREF0833_10874 2.9e-19 seryl-tRNA synthetase family protein; Psort location: Cytoplasmic, score: 7.50. | 0.616 |
| clpX | KXA28955.1 | HMPREF3229_01622 | HMPREF3229_01587 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Endopeptidase Clp; KEGG: bcr:BCAH187_A4003 1.6e-43 Clp protease. | 0.983 |
| clpX | clpP | HMPREF3229_01622 | HMPREF3229_01621 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.998 |
| clpX | engB | HMPREF3229_01622 | HMPREF3229_01624 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.707 |
| clpX | ftsH_1 | HMPREF3229_01622 | HMPREF3229_00750 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.645 |
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