STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfkNKEGG: rho:RHOM_15950 1.0e-112 5'-nucleotidase domain-containing protein; K01119 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Psort location: Cellwall, score: 8.97; Belongs to the 5'-nucleotidase family. (479 aa)    
Predicted Functional Partners:
phnE_1
KEGG: crn:CAR_c20670 2.1e-87 phosphonate ABC transporter permease K02042; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.940
phnE_2
KEGG: crn:CAR_c20660 1.5e-79 phosphonate ABC transporter permease K02042; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.940
metN_2
Phosphonate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
 
   
 0.939
KXA28641.1
KEGG: crn:CAR_c20640 5.3e-107 phosphonate ABC transporter substrate-binding protein K02044.
 
   
 0.921
punA
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.610
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.585
rlmCD
23S rRNA (uracil-5-)-methyltransferase RumA; KEGG: aoe:Clos_0725 6.8e-130 RNA methyltransferase; K00599; Psort location: Cytoplasmic, score: 7.50; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
       0.441
KXA31602.1
KEGG: fma:FMG_1186 2.3e-35 5-formyltetrahydrofolate cyclo-ligase; K01934 5-formyltetrahydrofolate cyclo-ligase; Psort location: Cytoplasmic, score: 7.50.
  
    0.404
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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