| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA28683.1 | clcA | HMPREF3229_01679 | HMPREF3229_01680 | Hypothetical protein; KEGG: apo:Arcpr_0662 0.0025 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 7.50. | Putative ATP synthase F0, A subunit; KEGG: cpr:CPR_1400 8.3e-86 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. | 0.773 |
| KXA28683.1 | mepA_5 | HMPREF3229_01679 | HMPREF3229_01678 | Hypothetical protein; KEGG: apo:Arcpr_0662 0.0025 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 7.50. | MATE efflux family protein; KEGG: rcp:RCAP_rcc02680 1.9e-14 mdtK; multidrug resistance protein MdtK K03327; Psort location: CytoplasmicMembrane, score: 10.00. | 0.511 |
| KXA28683.1 | nnr_2 | HMPREF3229_01679 | HMPREF3229_01677 | Hypothetical protein; KEGG: apo:Arcpr_0662 0.0025 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 7.50. | YjeF-like protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.511 |
| clcA | KXA28683.1 | HMPREF3229_01680 | HMPREF3229_01679 | Putative ATP synthase F0, A subunit; KEGG: cpr:CPR_1400 8.3e-86 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. | Hypothetical protein; KEGG: apo:Arcpr_0662 0.0025 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 7.50. | 0.773 |
| clcA | groL | HMPREF3229_01680 | HMPREF3229_01781 | Putative ATP synthase F0, A subunit; KEGG: cpr:CPR_1400 8.3e-86 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.434 |
| clcA | mepA_5 | HMPREF3229_01680 | HMPREF3229_01678 | Putative ATP synthase F0, A subunit; KEGG: cpr:CPR_1400 8.3e-86 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. | MATE efflux family protein; KEGG: rcp:RCAP_rcc02680 1.9e-14 mdtK; multidrug resistance protein MdtK K03327; Psort location: CytoplasmicMembrane, score: 10.00. | 0.588 |
| clcA | nnr_2 | HMPREF3229_01680 | HMPREF3229_01677 | Putative ATP synthase F0, A subunit; KEGG: cpr:CPR_1400 8.3e-86 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. | YjeF-like protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.599 |
| cshA | groL | HMPREF3229_00449 | HMPREF3229_01781 | KEGG: apr:Apre_1083 6.4e-134 DEAD/DEAH box helicase; K05592 ATP-dependent RNA helicase DeaD; Psort location: Cytoplasmic, score: 9.97. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.540 |
| cshA | nnr_2 | HMPREF3229_00449 | HMPREF3229_01677 | KEGG: apr:Apre_1083 6.4e-134 DEAD/DEAH box helicase; K05592 ATP-dependent RNA helicase DeaD; Psort location: Cytoplasmic, score: 9.97. | YjeF-like protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.992 |
| groL | clcA | HMPREF3229_01781 | HMPREF3229_01680 | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Putative ATP synthase F0, A subunit; KEGG: cpr:CPR_1400 8.3e-86 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. | 0.434 |
| groL | cshA | HMPREF3229_01781 | HMPREF3229_00449 | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | KEGG: apr:Apre_1083 6.4e-134 DEAD/DEAH box helicase; K05592 ATP-dependent RNA helicase DeaD; Psort location: Cytoplasmic, score: 9.97. | 0.540 |
| groL | nnr_1 | HMPREF3229_01781 | HMPREF3229_00622 | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Holo-[acyl-carrier-protein] synthase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | 0.488 |
| groL | nnr_2 | HMPREF3229_01781 | HMPREF3229_01677 | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | YjeF-like protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.452 |
| melR_1 | mepA_5 | HMPREF3229_01676 | HMPREF3229_01678 | Transcriptional regulator, AraC family; KEGG: ppo:PPM_0977 1.6e-14 yesN9; chemotaxis response regulator protein-glutamate methylesterase K07720. | MATE efflux family protein; KEGG: rcp:RCAP_rcc02680 1.9e-14 mdtK; multidrug resistance protein MdtK K03327; Psort location: CytoplasmicMembrane, score: 10.00. | 0.524 |
| melR_1 | nnr_2 | HMPREF3229_01676 | HMPREF3229_01677 | Transcriptional regulator, AraC family; KEGG: ppo:PPM_0977 1.6e-14 yesN9; chemotaxis response regulator protein-glutamate methylesterase K07720. | YjeF-like protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.400 |
| mepA_5 | KXA28683.1 | HMPREF3229_01678 | HMPREF3229_01679 | MATE efflux family protein; KEGG: rcp:RCAP_rcc02680 1.9e-14 mdtK; multidrug resistance protein MdtK K03327; Psort location: CytoplasmicMembrane, score: 10.00. | Hypothetical protein; KEGG: apo:Arcpr_0662 0.0025 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 7.50. | 0.511 |
| mepA_5 | clcA | HMPREF3229_01678 | HMPREF3229_01680 | MATE efflux family protein; KEGG: rcp:RCAP_rcc02680 1.9e-14 mdtK; multidrug resistance protein MdtK K03327; Psort location: CytoplasmicMembrane, score: 10.00. | Putative ATP synthase F0, A subunit; KEGG: cpr:CPR_1400 8.3e-86 chloride channel protein K01529; Psort location: CytoplasmicMembrane, score: 10.00. | 0.588 |
| mepA_5 | melR_1 | HMPREF3229_01678 | HMPREF3229_01676 | MATE efflux family protein; KEGG: rcp:RCAP_rcc02680 1.9e-14 mdtK; multidrug resistance protein MdtK K03327; Psort location: CytoplasmicMembrane, score: 10.00. | Transcriptional regulator, AraC family; KEGG: ppo:PPM_0977 1.6e-14 yesN9; chemotaxis response regulator protein-glutamate methylesterase K07720. | 0.524 |
| mepA_5 | nnr_2 | HMPREF3229_01678 | HMPREF3229_01677 | MATE efflux family protein; KEGG: rcp:RCAP_rcc02680 1.9e-14 mdtK; multidrug resistance protein MdtK K03327; Psort location: CytoplasmicMembrane, score: 10.00. | YjeF-like protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.779 |
| nnr_1 | groL | HMPREF3229_00622 | HMPREF3229_01781 | Holo-[acyl-carrier-protein] synthase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.488 |