| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA28689.1 | ttcA | HMPREF3229_01685 | HMPREF3229_01684 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | 0.525 |
| csd | ttcA | HMPREF3229_00077 | HMPREF3229_01684 | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | 0.665 |
| hemZ_2 | ttcA | HMPREF3229_00894 | HMPREF3229_01684 | Radical SAM protein family; KEGG: ctc:CTC01244 1.1e-76 oxygen-independent coproporphyrinogen III oxidase K00540; Psort location: Cytoplasmic, score: 7.50. | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | 0.493 |
| lysS | trmB | HMPREF3229_00500 | HMPREF3229_01763 | lysine--tRNA ligase; KEGG: fma:FMG_0987 2.5e-251 lysyl-tRNA synthetase class II; K04567 lysyl-tRNA synthetase, class II; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.425 |
| lysS | ttcA | HMPREF3229_00500 | HMPREF3229_01684 | lysine--tRNA ligase; KEGG: fma:FMG_0987 2.5e-251 lysyl-tRNA synthetase class II; K04567 lysyl-tRNA synthetase, class II; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | 0.487 |
| lysS | typA | HMPREF3229_00500 | HMPREF3229_00554 | lysine--tRNA ligase; KEGG: fma:FMG_0987 2.5e-251 lysyl-tRNA synthetase class II; K04567 lysyl-tRNA synthetase, class II; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. | KEGG: cch:Cag_1518 1.4e-177 GTP-binding protein TypA K06207; Psort location: CytoplasmicMembrane, score: 8.78. | 0.447 |
| mfd | pth | HMPREF3229_00295 | HMPREF3229_00296 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.941 |
| mfd | ttcA | HMPREF3229_00295 | HMPREF3229_01684 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | 0.565 |
| norV | ttcA | HMPREF3229_01683 | HMPREF3229_01684 | Metallo-beta-lactamase domain protein; KEGG: rci:RCIX2263 2.0e-59 fprA-2; F420H2 oxidase; Psort location: Cytoplasmic, score: 9.97. | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | 0.546 |
| pth | mfd | HMPREF3229_00296 | HMPREF3229_00295 | aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.941 |
| pth | ttcA | HMPREF3229_00296 | HMPREF3229_01684 | aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | 0.612 |
| sulD | ttcA | HMPREF3229_00742 | HMPREF3229_01684 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | 0.519 |
| trmB | lysS | HMPREF3229_01763 | HMPREF3229_00500 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | lysine--tRNA ligase; KEGG: fma:FMG_0987 2.5e-251 lysyl-tRNA synthetase class II; K04567 lysyl-tRNA synthetase, class II; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.425 |
| trmB | ttcA | HMPREF3229_01763 | HMPREF3229_01684 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | 0.469 |
| ttcA | KXA28689.1 | HMPREF3229_01684 | HMPREF3229_01685 | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.525 |
| ttcA | csd | HMPREF3229_01684 | HMPREF3229_00077 | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.665 |
| ttcA | hemZ_2 | HMPREF3229_01684 | HMPREF3229_00894 | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | Radical SAM protein family; KEGG: ctc:CTC01244 1.1e-76 oxygen-independent coproporphyrinogen III oxidase K00540; Psort location: Cytoplasmic, score: 7.50. | 0.493 |
| ttcA | lysS | HMPREF3229_01684 | HMPREF3229_00500 | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | lysine--tRNA ligase; KEGG: fma:FMG_0987 2.5e-251 lysyl-tRNA synthetase class II; K04567 lysyl-tRNA synthetase, class II; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.487 |
| ttcA | mfd | HMPREF3229_01684 | HMPREF3229_00295 | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.565 |
| ttcA | norV | HMPREF3229_01684 | HMPREF3229_01683 | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | Metallo-beta-lactamase domain protein; KEGG: rci:RCIX2263 2.0e-59 fprA-2; F420H2 oxidase; Psort location: Cytoplasmic, score: 9.97. | 0.546 |