| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXA28689.1 | KXA29492.1 | HMPREF3229_01685 | HMPREF3229_01116 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | KEGG: ccm:Ccan_14080 1.8e-35 capsule biosynthesis protein capA K07282; Psort location: CytoplasmicMembrane, score: 9.68. | 0.657 |
| KXA28689.1 | KXA31421.1 | HMPREF3229_01685 | HMPREF3229_00405 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein; KEGG: llr:llh_1575 1.7e-30 nicotinamidase; Psort location: Cytoplasmic, score: 7.50. | 0.953 |
| KXA28689.1 | nadC_2 | HMPREF3229_01685 | HMPREF3229_00240 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | KEGG: fnu:FN0010 4.2e-91 nicotinate-nucleotide pyrophosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | 0.977 |
| KXA28689.1 | nadD | HMPREF3229_01685 | HMPREF3229_00112 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.943 |
| KXA28689.1 | nadE | HMPREF3229_01685 | HMPREF3229_00056 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.623 |
| KXA28689.1 | porA | HMPREF3229_01685 | HMPREF3229_00890 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | KEGG: fma:FMG_0385 0. pyruvate/ferredoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 7.50. | 0.562 |
| KXA28689.1 | punA | HMPREF3229_01685 | HMPREF3229_00784 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.913 |
| KXA28689.1 | surE_3 | HMPREF3229_01685 | HMPREF3229_00332 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.907 |
| KXA28689.1 | ttcA | HMPREF3229_01685 | HMPREF3229_01684 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | PP-loop family protein; KEGG: fbl:Fbal_1913 3.4e-32 tRNA s(2)C-32 sulfurtransferase K14058; Psort location: Cytoplasmic, score: 7.50; Belongs to the TtcA family. | 0.525 |
| KXA28689.1 | yfaY | HMPREF3229_01685 | HMPREF3229_01158 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 5.6e-13 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 7.50; Belongs to the CinA family. | 0.610 |
| KXA29492.1 | KXA28689.1 | HMPREF3229_01116 | HMPREF3229_01685 | KEGG: ccm:Ccan_14080 1.8e-35 capsule biosynthesis protein capA K07282; Psort location: CytoplasmicMembrane, score: 9.68. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.657 |
| KXA31421.1 | KXA28689.1 | HMPREF3229_00405 | HMPREF3229_01685 | Hypothetical protein; KEGG: llr:llh_1575 1.7e-30 nicotinamidase; Psort location: Cytoplasmic, score: 7.50. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.953 |
| KXA31421.1 | punA | HMPREF3229_00405 | HMPREF3229_00784 | Hypothetical protein; KEGG: llr:llh_1575 1.7e-30 nicotinamidase; Psort location: Cytoplasmic, score: 7.50. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.906 |
| nadC_2 | KXA28689.1 | HMPREF3229_00240 | HMPREF3229_01685 | KEGG: fnu:FN0010 4.2e-91 nicotinate-nucleotide pyrophosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.977 |
| nadC_2 | nadD | HMPREF3229_00240 | HMPREF3229_00112 | KEGG: fnu:FN0010 4.2e-91 nicotinate-nucleotide pyrophosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.935 |
| nadC_2 | surE_3 | HMPREF3229_00240 | HMPREF3229_00332 | KEGG: fnu:FN0010 4.2e-91 nicotinate-nucleotide pyrophosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.905 |
| nadC_2 | yfaY | HMPREF3229_00240 | HMPREF3229_01158 | KEGG: fnu:FN0010 4.2e-91 nicotinate-nucleotide pyrophosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 5.6e-13 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 7.50; Belongs to the CinA family. | 0.549 |
| nadD | KXA28689.1 | HMPREF3229_00112 | HMPREF3229_01685 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.943 |
| nadD | nadC_2 | HMPREF3229_00112 | HMPREF3229_00240 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | KEGG: fnu:FN0010 4.2e-91 nicotinate-nucleotide pyrophosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | 0.935 |
| nadD | nadE | HMPREF3229_00112 | HMPREF3229_00056 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.943 |