Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
trxB_1KEGG: thx:Thet_1993 1.4e-92 thioredoxin reductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 9.97. (316 aa)    
Predicted Functional Partners:
csd
Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
  0.918
trxB_2
KEGG: dai:Desaci_3389 3.6e-76 thioredoxin-disulfide reductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 9.97.
  
  
 
0.909
ahpC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.821
trxA
Thioredoxin; KEGG: sis:LS215_0050 2.5e-08 thioredoxin K03671; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.813
resA_2
Redoxin family protein; KEGG: aca:ACP_1678 1.6e-11 thiol-disulfide oxidoreductase.
  
 
 0.743
KXA28536.1
Hypothetical protein; KEGG: ccb:Clocel_1853 2.5e-05 multi-sensor signal transduction histidine kinase; K07636 two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Psort location: CytoplasmicMembrane, score: 10.00.
       0.556
cysS
cysteine--tRNA ligase; KEGG: fma:FMG_0415 7.2e-158 cysteinyl-tRNA synthetase; K01883 cysteinyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.538
moeZ
ThiF family protein; KEGG: bpb:bpr_I2644 1.1e-42 thiF; thiamine biosynthesis protein ThiF.
  
    0.501
msrAB
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.494
porA
KEGG: fma:FMG_0385 0. pyruvate/ferredoxin oxidoreductase; K03737 putative pyruvate-flavodoxin oxidoreductase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.484
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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