| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA | cueR | HMPREF3229_01815 | HMPREF3229_01806 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | 0.608 |
| birA | rpoA | HMPREF3229_01815 | HMPREF3229_01759 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.454 |
| birA | rpoD | HMPREF3229_01815 | HMPREF3229_01237 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.402 |
| cbpA | cueR | HMPREF3229_00587 | HMPREF3229_01806 | DnaJ domain protein; KEGG: apb:SAR116_1614 3.3e-34 DnaJ family molecular chaperone K03686; Psort location: Cytoplasmic, score: 9.67. | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | 0.873 |
| copA | cueR | HMPREF3229_00699 | HMPREF3229_01806 | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | 0.625 |
| cueR | birA | HMPREF3229_01806 | HMPREF3229_01815 | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.608 |
| cueR | cbpA | HMPREF3229_01806 | HMPREF3229_00587 | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | DnaJ domain protein; KEGG: apb:SAR116_1614 3.3e-34 DnaJ family molecular chaperone K03686; Psort location: Cytoplasmic, score: 9.67. | 0.873 |
| cueR | copA | HMPREF3229_01806 | HMPREF3229_00699 | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | Copper-exporting ATPase; KEGG: apr:Apre_0987 8.9e-264 heavy metal translocating P-type ATPase; K01533 Cu2+-exporting ATPase; Psort location: CytoplasmicMembrane, score: 9.99. | 0.625 |
| cueR | dnaJ_1 | HMPREF3229_01806 | HMPREF3229_01540 | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | DnaJ domain protein; KEGG: cre:CHLREDRAFT_195902 0.00027 DNJ3; DnaJ-like protein; K09584 protein disulfide-isomerase A6; Psort location: CytoplasmicMembrane, score: 9.55. | 0.873 |
| cueR | dnaJ_2 | HMPREF3229_01806 | HMPREF3229_01263 | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.873 |
| cueR | rpoA | HMPREF3229_01806 | HMPREF3229_01759 | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.896 |
| cueR | rpoB | HMPREF3229_01806 | HMPREF3229_00353 | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.949 |
| cueR | rpoC | HMPREF3229_01806 | HMPREF3229_00354 | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.881 |
| cueR | rpoD | HMPREF3229_01806 | HMPREF3229_01237 | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.920 |
| cueR | rpoZ | HMPREF3229_01806 | HMPREF3229_00947 | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.885 |
| dnaJ_1 | cueR | HMPREF3229_01540 | HMPREF3229_01806 | DnaJ domain protein; KEGG: cre:CHLREDRAFT_195902 0.00027 DNJ3; DnaJ-like protein; K09584 protein disulfide-isomerase A6; Psort location: CytoplasmicMembrane, score: 9.55. | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | 0.873 |
| dnaJ_1 | dnaJ_2 | HMPREF3229_01540 | HMPREF3229_01263 | DnaJ domain protein; KEGG: cre:CHLREDRAFT_195902 0.00027 DNJ3; DnaJ-like protein; K09584 protein disulfide-isomerase A6; Psort location: CytoplasmicMembrane, score: 9.55. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.714 |
| dnaJ_2 | cueR | HMPREF3229_01263 | HMPREF3229_01806 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 1.3e-07 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50. | 0.873 |
| dnaJ_2 | dnaJ_1 | HMPREF3229_01263 | HMPREF3229_01540 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | DnaJ domain protein; KEGG: cre:CHLREDRAFT_195902 0.00027 DNJ3; DnaJ-like protein; K09584 protein disulfide-isomerase A6; Psort location: CytoplasmicMembrane, score: 9.55. | 0.714 |
| dnaJ_2 | rpoD | HMPREF3229_01263 | HMPREF3229_01237 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.473 |