Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
tplPSP1 protein; KEGG: gka:GK0026 6.2e-81 signal peptidase II; Psort location: Cytoplasmic, score: 7.50. (297 aa)    
Predicted Functional Partners:
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
    0.950
rny
YmdA/YtgF family protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
 
  
 0.850
KXA27743.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
    0.846
dnaX_1
Hypothetical protein; KEGG: aoe:Clos_0062 1.8e-42 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97.
  
   0.838
KXA27742.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
    0.821
speA
Orn/Lys/Arg decarboxylase, major domain protein; KEGG: ttm:Tthe_0076 6.5e-70 Orn/Lys/Arg decarboxylase major subunit; K01582 lysine decarboxylase; Psort location: Cytoplasmic, score: 9.97.
  
    0.818
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
     0.809
KXA27739.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.35.
 
     0.745
metG_1
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
      0.739
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.683
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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