STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fhs_3KEGG: faa:HMPREF0389_01605 1.2e-205 formate--tetrahydrofolate ligase; K01938 formate--tetrahydrofolate ligase; Psort location: Cytoplasmic, score: 7.50. (559 aa)    
Predicted Functional Partners:
folD
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
 
 0.971
fchA_3
Putative methenyltetrahydrofolate cyclohydrolase; KEGG: ctc:CTC02303 2.7e-48 formiminotetrahydrofolate cyclodeaminase K01746; Psort location: Cytoplasmic, score: 9.97.
    
 0.905
purL
KEGG: apr:Apre_1107 0. phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.903
KXA27790.1
KEGG: ctc:CTC02305 2.2e-101 glutamate formiminotransferase K00603; Psort location: Cytoplasmic, score: 7.50.
       0.795
KXA27787.1
Hypothetical protein; KEGG: fnu:FN1854 5.3e-91 methylaspartate mutase K01846; Psort location: Cytoplasmic, score: 7.50.
  
    0.759
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.758
purH
KEGG: tmt:Tmath_0637 1.1e-138 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.754
purC
KEGG: faa:HMPREF0389_00399 6.9e-66 phosphoribosylaminoimidazole-succinocarboxamide synthase; K01923 phosphoribosylaminoimidazole-succinocarboxamide synthase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.733
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
 
      0.713
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
  
 0.712
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
Server load: low (10%) [HD]