Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXA27812.1KEGG: ddf:DEFDS_1615 2.6e-114 thiC; thiamine biosynthesis protein ThiC K03147; Psort location: Cytoplasmic, score: 7.50. (433 aa)    
Predicted Functional Partners:
KXA27810.1
KEGG: ccl:Clocl_3523 2.8e-62 phosphomethylpyrimidine kinase; K00941 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.966
KXA28532.1
Iron-only hydrogenase maturation rSAM protein HydG; KEGG: hor:Hore_19320 1.2e-111 thiH; thiamine biosynthesis protein ThiH K03150; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.871
KXA27809.1
KEGG: gvg:HMPREF0421_20554 5.1e-38 thiM2; hydroxyethylthiazole kinase K00878; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.859
moeZ
ThiF family protein; KEGG: bpb:bpr_I2644 1.1e-42 thiF; thiamine biosynthesis protein ThiF.
  
  
 0.739
KXA27811.1
Protein ThiW; KEGG: cpy:Cphy_3701 3.5e-07 heptaprenyl diphosphate synthase component I; K00805 heptaprenyl diphosphate synthase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.522
sulD
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.495
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
      
 0.476
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.454
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
       0.435
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
  
 0.425
Your Current Organism:
Peptoniphilus harei
NCBI taxonomy Id: 54005
Other names: ATCC BAA-601, CCUG 38491, CIP 105323, DSM 10020, NCTC 13076, P. harei, Peptostreptococcus harei, Schleiferella harei
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