STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (229 aa)    
Predicted Functional Partners:
CUX76955.1
Cob(I)alamin adenosyltransferase.
 
 
 0.972
CUX76898.1
Predicted adenosylcobinamide-phosphate guanylyltransferase CobY.
 
  
 0.964
CUX77436.1
ATP:Cob(I)alamin adenosyltransferase.
    
 0.946
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.918
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.916
CUX77332.1
Putative activity regulator of membrane protease YbbK.
 
    0.898
CUX78047.1
Predicted alpha-ribazole-5'-phosphate phosphatase CobZ.
 
  
  0.863
CUX78053.1
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Belongs to the UPF0284 family.
 
  
 0.790
CUX78049.1
Hypothetical protein.
       0.773
CUX78042.1
L-threonine 3-O-phosphate decarboxylase.
 
   
 0.719
Your Current Organism:
Thermococcus chitonophagus
NCBI taxonomy Id: 54262
Other names: DSM 10152, T. chitonophagus, strain GC74
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