TEA_027497 protein (Camellia sinensis) - STRING interaction network

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Score

TEA_027497

BHLH domain-containing protein. (146 aa)

Predicted Functional Partners:

TEA_016556

0.999

TEA_003220

0.997

TEA_028360

0.954

TEA_010444

0.954

TEA_014599

0.949

TEA_004738

0.947

TEA_003102

0.947

TEA_000420

0.946

TEA_010109

0.935

TEA_018294

0.935

Your Current Organism:

Camellia sinensis

NCBI taxonomy Id: 542762
Other names: C. sinensis var. sinensis, Camellia sinensis var. sinensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TEA_000420	TEA_003220	A0A4S4E8Q2	A0A4S4DWQ8	DNA ligase.	Uncharacterized protein.	0.972
TEA_000420	TEA_014599	A0A4S4E8Q2	A0A4S4E2Y8	DNA ligase.	DNA ligase.	0.932
TEA_000420	TEA_016556	A0A4S4E8Q2	A0A4S4EXN9	DNA ligase.	BRCT domain-containing protein.	0.987
TEA_000420	TEA_027497	A0A4S4E8Q2	A0A4S4DUR0	DNA ligase.	BHLH domain-containing protein.	0.946
TEA_003102	TEA_010109	A0A4S4EV91	A0A4S4DP88	FHA domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.982
TEA_003102	TEA_018294	A0A4S4EV91	A0A4S4EGW3	FHA domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.982
TEA_003102	TEA_027497	A0A4S4EV91	A0A4S4DUR0	FHA domain-containing protein.	BHLH domain-containing protein.	0.947
TEA_003220	TEA_000420	A0A4S4DWQ8	A0A4S4E8Q2	Uncharacterized protein.	DNA ligase.	0.972
TEA_003220	TEA_014599	A0A4S4DWQ8	A0A4S4E2Y8	Uncharacterized protein.	DNA ligase.	0.999
TEA_003220	TEA_016556	A0A4S4DWQ8	A0A4S4EXN9	Uncharacterized protein.	BRCT domain-containing protein.	0.505
TEA_003220	TEA_027497	A0A4S4DWQ8	A0A4S4DUR0	Uncharacterized protein.	BHLH domain-containing protein.	0.997
TEA_004738	TEA_010109	A0A4S4EE75	A0A4S4DP88	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. In the C-terminal section; belongs to the HisA/HisF family.	Aminotran_1_2 domain-containing protein.	0.982
TEA_004738	TEA_018294	A0A4S4EE75	A0A4S4EGW3	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. In the C-terminal section; belongs to the HisA/HisF family.	Aminotran_1_2 domain-containing protein.	0.982
TEA_004738	TEA_027497	A0A4S4EE75	A0A4S4DUR0	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. In the C-terminal section; belongs to the HisA/HisF family.	BHLH domain-containing protein.	0.947
TEA_010109	TEA_003102	A0A4S4DP88	A0A4S4EV91	Aminotran_1_2 domain-containing protein.	FHA domain-containing protein.	0.982
TEA_010109	TEA_004738	A0A4S4DP88	A0A4S4EE75	Aminotran_1_2 domain-containing protein.	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. In the C-terminal section; belongs to the HisA/HisF family.	0.982
TEA_010109	TEA_027497	A0A4S4DP88	A0A4S4DUR0	Aminotran_1_2 domain-containing protein.	BHLH domain-containing protein.	0.935
TEA_010444	TEA_027497	A0A4S4DP52	A0A4S4DUR0	Uncharacterized protein.	BHLH domain-containing protein.	0.954
TEA_010444	TEA_028360	A0A4S4DP52	A0A4S4D8Y4	Uncharacterized protein.	Fucokinase domain-containing protein.	0.974
TEA_014599	TEA_000420	A0A4S4E2Y8	A0A4S4E8Q2	DNA ligase.	DNA ligase.	0.932

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Network Stats

number of nodes:

11

number of edges:

49

average node degree:

8.91

avg. local clustering coefficient:

0.899

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042438

Melanin biosynthetic process

6 of 17

2.41

4.67

4.27e-10

GO:0043473

Pigmentation

2 of 2

2.86

1.39

0.0030

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004503

Tyrosinase activity

4 of 7

2.62

3.21

9.56e-07

GO:0004497

Monooxygenase activity

6 of 211

1.32

1.39

7.60e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045009

Chitosome

2 of 3

2.69

1.02

0.0139

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6990

Tyrosinase copper-binding domain, and Cytochrome b561/ferric reductase transmembrane

8 of 11

2.73

8.28

4.61e-17

CL:6994

Tyrosinase copper-binding domain

5 of 5

2.86

5.28

1.33e-10

CL:786

RNA Polymerase II Pre-transcription Events, and Tyrosinase activity

3 of 86

1.41

0.63

0.0467

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00350

Tyrosine metabolism

11 of 89

1.96

6.28

9.48e-20

map01110

Biosynthesis of secondary metabolites

11 of 866

0.97

1.19

1.86e-09

map01100

Metabolic pathways

11 of 2708

0.47

0.4

0.00033

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5662702

Melanin biosynthesis

2 of 2

2.86

1.12

0.0096

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0033162

Melanosome membrane

3 of 4

2.74

2.29

6.30e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0479

Metal-binding

9 of 550

1.08

1.3

4.18e-07

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00264

Common central domain of tyrosinase

9 of 12

2.74

9.71

3.79e-20

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR008922

Di-copper centre-containing domain superfamily

9 of 12

2.74

9.5

1.12e-19

IPR002227

Tyrosinase copper-binding domain

9 of 12

2.74

9.5

1.12e-19

IPR041640

Tyosinase, C-terminal

2 of 2

2.86

1.13

0.0091

IPR040632

Sulfotransferase, S. mansonii-type

2 of 5

2.47

0.89

0.0239

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