TEA_019139 protein (Camellia sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TEA_019139

NmrA domain-containing protein. (398 aa)

Predicted Functional Partners:

TEA_022229

0.911

TEA_022225

0.911

TEA_014156

0.897

TEA_014163

0.897

TEA_008282

0.569

TEA_020540

0.569

TEA_020356

0.518

TEA_002944

0.513

TEA_025936

0.513

TEA_006882

0.513

Your Current Organism:

Camellia sinensis

NCBI taxonomy Id: 542762
Other names: C. sinensis var. sinensis, Camellia sinensis var. sinensis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TEA_002944	TEA_014156	A0A4S4CXV9	A0A4S4DSG5	3Beta_HSD domain-containing protein.	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	0.752
TEA_002944	TEA_014163	A0A4S4CXV9	A0A4V3WLV0	3Beta_HSD domain-containing protein.	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	0.752
TEA_002944	TEA_019139	A0A4S4CXV9	A0A4S4EQJ5	3Beta_HSD domain-containing protein.	NmrA domain-containing protein.	0.513
TEA_006882	TEA_014156	A0A4S4DSZ0	A0A4S4DSG5	Epimerase domain-containing protein.	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	0.752
TEA_006882	TEA_014163	A0A4S4DSZ0	A0A4V3WLV0	Epimerase domain-containing protein.	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	0.752
TEA_006882	TEA_019139	A0A4S4DSZ0	A0A4S4EQJ5	Epimerase domain-containing protein.	NmrA domain-containing protein.	0.513
TEA_008282	TEA_014156	A0A4S4D9W3	A0A4S4DSG5	Epimerase domain-containing protein.	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	0.893
TEA_008282	TEA_014163	A0A4S4D9W3	A0A4V3WLV0	Epimerase domain-containing protein.	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	0.893
TEA_008282	TEA_019139	A0A4S4D9W3	A0A4S4EQJ5	Epimerase domain-containing protein.	NmrA domain-containing protein.	0.569
TEA_014156	TEA_002944	A0A4S4DSG5	A0A4S4CXV9	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	3Beta_HSD domain-containing protein.	0.752
TEA_014156	TEA_006882	A0A4S4DSG5	A0A4S4DSZ0	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Epimerase domain-containing protein.	0.752
TEA_014156	TEA_008282	A0A4S4DSG5	A0A4S4D9W3	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Epimerase domain-containing protein.	0.893
TEA_014156	TEA_019139	A0A4S4DSG5	A0A4S4EQJ5	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	NmrA domain-containing protein.	0.897
TEA_014156	TEA_020356	A0A4S4DSG5	A0A4S4F1X0	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Uncharacterized protein.	0.478
TEA_014156	TEA_020540	A0A4S4DSG5	A0A4S4EWX7	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Epimerase domain-containing protein.	0.893
TEA_014156	TEA_022225	A0A4S4DSG5	A0A4S4D7I6	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Epimerase domain-containing protein.	0.947
TEA_014156	TEA_022229	A0A4S4DSG5	A0A4S4D6J7	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Epimerase domain-containing protein.	0.947
TEA_014156	TEA_025936	A0A4S4DSG5	A0A4S4CYY7	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	NAD(P)-bd_dom domain-containing protein.	0.752
TEA_014163	TEA_002944	A0A4V3WLV0	A0A4S4CXV9	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	3Beta_HSD domain-containing protein.	0.752
TEA_014163	TEA_006882	A0A4V3WLV0	A0A4S4DSZ0	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.	Epimerase domain-containing protein.	0.752

page 1 of 3

Network Stats

number of nodes:

9

number of edges:

19

average node degree:

4.22

avg. local clustering coefficient:

0.858

expected number of edges:

9

PPI enrichment p-value:

0.00314

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006914

Autophagy

5 of 90

1.7

1.88

8.13e-05

GO:0061709

Reticulophagy

2 of 4

2.66

1.02

0.0187

GO:0016236

Macroautophagy

3 of 46

1.77

0.93

0.0187

GO:0000422

Autophagy of mitochondrion

2 of 8

2.35

0.89

0.0289

GO:0034727

Piecemeal microautophagy of the nucleus

2 of 14

2.11

0.75

0.0495

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000407

Phagophore assembly site

4 of 25

2.16

2.64

1.04e-05

GO:0034045

Phagophore assembly site membrane

3 of 13

2.32

2.15

0.00014

GO:0005773

Vacuole

6 of 186

1.46

1.83

1.04e-05

GO:0005776

Autophagosome

2 of 2

2.96

1.7

0.0013

GO:0005774

Vacuolar membrane

4 of 133

1.43

1.22

0.0015

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:11059

Mixed, incl. Autophagy - other, and Organic cation transport

6 of 37

2.17

4.3

1.61e-09

CL:11064

Autophagy - other, and Lipase (class 3)

4 of 23

2.2

2.87

3.83e-06

CL:11096

Atg1/ULK1 kinase complex, and Phagophore assembly site

3 of 7

2.59

2.64

2.39e-05

CL:11119

Mixed, incl. Peptidase M18, and Lysosomal oligosaccharide catabolism

2 of 7

2.41

1.24

0.0071

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04136

Autophagy - other

4 of 23

2.2

3.03

1.72e-06

map04138

Autophagy - yeast

4 of 98

1.57

1.61

0.00020

map04139

Mitophagy - yeast

3 of 48

1.75

1.51

0.00091

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9612973

Autophagy

5 of 60

1.88

2.59

3.13e-06

MAP-1632852

Macroautophagy

5 of 60

1.88

2.59

3.13e-06

MAP-9663891

Selective autophagy

3 of 30

1.96

1.51

0.0015

MAP-8934903

Receptor Mediated Mitophagy

2 of 9

2.3

1.07

0.0137

MAP-5205647

Mitophagy

2 of 19

1.98

0.78

0.0415

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0034045

Phagophore assembly site membrane

3 of 15

2.26

1.76

0.00073

GOCC:0005776

Autophagosome

2 of 2

2.96

1.58

0.0021

GOCC:0034270

Cvt complex

2 of 3

2.78

1.52

0.0026

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0072

Autophagy

2 of 9

2.3

1.08

0.0132

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (12%) [HD]

Permalink

Credits

Access

Info

About

STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About