TEA_011534 protein (Camellia sinensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

TEA_011534

Uncharacterized protein. (177 aa)

Predicted Functional Partners:

TEA_018895

0.983

TEA_018892

0.983

TEA_007552

0.982

TEA_027873

0.979

TEA_025553

0.966

TEA_026867

0.965

TEA_004023

0.963

TEA_027871

0.959

TEA_024236

0.953

TEA_005568

0.953

Your Current Organism:

Camellia sinensis

NCBI taxonomy Id: 542762
Other names: C. sinensis var. sinensis, Camellia sinensis var. sinensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TEA_004023	TEA_005568	A0A4S4DDV1	A0A4S4ETG4	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.994
TEA_004023	TEA_007552	A0A4S4DDV1	A0A4S4D7Q9	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.999
TEA_004023	TEA_011534	A0A4S4DDV1	A0A4V3WR28	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.963
TEA_004023	TEA_018892	A0A4S4DDV1	A0A4S4DJF9	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	C2H2-type domain-containing protein.	0.993
TEA_004023	TEA_018895	A0A4S4DDV1	A0A4S4DJC6	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	C2H2-type domain-containing protein.	0.993
TEA_004023	TEA_024236	A0A4S4DDV1	A0A4S4DX47	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.994
TEA_004023	TEA_025553	A0A4S4DDV1	A0A4S4D488	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.999
TEA_004023	TEA_026867	A0A4S4DDV1	A0A4S4E9D1	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	DUF5311 domain-containing protein.	0.999
TEA_004023	TEA_027871	A0A4S4DDV1	A0A4S4D9G3	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.998
TEA_004023	TEA_027873	A0A4S4DDV1	A0A4V3WK13	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	Uncharacterized protein.	0.999
TEA_005568	TEA_004023	A0A4S4ETG4	A0A4S4DDV1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.994
TEA_005568	TEA_007552	A0A4S4ETG4	A0A4S4D7Q9	Uncharacterized protein.	Uncharacterized protein.	0.996
TEA_005568	TEA_011534	A0A4S4ETG4	A0A4V3WR28	Uncharacterized protein.	Uncharacterized protein.	0.953
TEA_005568	TEA_018892	A0A4S4ETG4	A0A4S4DJF9	Uncharacterized protein.	C2H2-type domain-containing protein.	0.979
TEA_005568	TEA_018895	A0A4S4ETG4	A0A4S4DJC6	Uncharacterized protein.	C2H2-type domain-containing protein.	0.979
TEA_005568	TEA_024236	A0A4S4ETG4	A0A4S4DX47	Uncharacterized protein.	Uncharacterized protein.	0.899
TEA_005568	TEA_025553	A0A4S4ETG4	A0A4S4D488	Uncharacterized protein.	Uncharacterized protein.	0.999
TEA_005568	TEA_026867	A0A4S4ETG4	A0A4S4E9D1	Uncharacterized protein.	DUF5311 domain-containing protein.	0.993
TEA_005568	TEA_027871	A0A4S4ETG4	A0A4S4D9G3	Uncharacterized protein.	Uncharacterized protein.	0.980
TEA_005568	TEA_027873	A0A4S4ETG4	A0A4V3WK13	Uncharacterized protein.	Uncharacterized protein.	0.995

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Network Stats

number of nodes:

11

number of edges:

45

average node degree:

8.18

avg. local clustering coefficient:

0.761

expected number of edges:

12

PPI enrichment p-value:

9.59e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0018105

Peptidyl-serine phosphorylation

3 of 90

1.9

1.1

0.0072

GO:0071218

Cellular response to misfolded protein

2 of 19

2.4

0.99

0.0155

GO:0051247

Positive regulation of protein metabolic process

3 of 135

1.73

0.96

0.0118

GO:0006515

Protein quality control for misfolded or incompletely synthesized proteins

2 of 43

2.05

0.73

0.0434

GO:0045862

Positive regulation of proteolysis

2 of 57

1.93

0.71

0.0450

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004842

Ubiquitin-protein transferase activity

4 of 422

1.36

0.82

0.0137

GO:0061630

Ubiquitin protein ligase activity

3 of 225

1.51

0.74

0.0291

GO:0140096

Catalytic activity, acting on a protein

9 of 3324

0.81

0.69

0.00053

GO:0016740

Transferase activity

10 of 4634

0.71

0.6

0.00053

GO:0016301

Kinase activity

6 of 1874

0.89

0.56

0.0178

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005776

Autophagosome

2 of 22

2.34

0.79

0.0353

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:13820

Mixed, incl. Ubiquitin conjugating enzyme activity, and Ubiquitin homologues

3 of 84

1.93

0.83

0.0263

CL:20418

Mixed, incl. MAP kinase activity, and Rho (Ras homology) subfamily of Ras-like small GTPases

2 of 21

2.36

0.82

0.0312

CL:35943

Autophagy - other

2 of 23

2.32

0.82

0.0317

CL:13925

Ubiquitin conjugating enzyme activity, and Lipid desaturase domain

2 of 27

2.25

0.78

0.0375

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005776

Autophagosome

2 of 17

2.45

0.81

0.0341

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR045202

CHIP , U-box domain

2 of 2

3.38

1.25

0.0056

IPR045200

E3 ubiquitin-protein ligase CHIP

2 of 2

3.38

1.25

0.0056

IPR000433

Zinc finger, ZZ-type

2 of 8

2.78

1.03

0.0139

IPR043145

Zinc finger, ZZ-type superfamily

2 of 9

2.73

1.02

0.0139

IPR027370

Zinc finger, RING-type, eukaryotic

2 of 12

2.6

0.98

0.0168

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00028

Tetratricopeptide repeats

3 of 67

2.03

1.47

0.0014

SM00291

Zinc-binding domain, present in Dystrophin, CREB-binding protein.

2 of 15

2.51

1.25

0.0052

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