STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DD237_00809753EXOc domain-containing protein. (229 aa)    
Predicted Functional Partners:
DD238_002342
Uncharacterized protein.
   
 
 0.983
DD237_007080
POLAc domain-containing protein.
 
      0.899
DD238_002135
Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.
   
 0.743
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 
 0.733
DD238_002684
AAA_23 domain-containing protein.
  
 
 0.690
DD237_004116
PMSR domain-containing protein.
   
  
 0.676
DD237_001097
Uncharacterized protein.
  
 
 0.662
DD238_006157
Uncharacterized protein.
  
 
 0.662
DD238_007688
Uncharacterized protein.
   
 0.662
DD238_004527
Uncharacterized protein.
  
 
 0.662
Your Current Organism:
Peronospora effusa
NCBI taxonomy Id: 542832
Other names: P. effusa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.