STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (251 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
 0.948
ydiB_1
Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.946
ydiB_2
Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.945
AJF71194.1
Catalyzes the conversion of shikimate to 3-dehydroshikimate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.934
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
    
 0.922
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
    
 0.920
quiA_2
Glucose dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.904
quiA_1
Glucose dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.904
entC
Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.821
menF
Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
     
 0.821
Your Current Organism:
Raoultella ornithinolytica
NCBI taxonomy Id: 54291
Other names: ATCC 31898, CCUG 26769, CIP 103364, CIP 103576, DSM 7464, JCM 6096, Klebsiella ornithinolytica, Klebsiella sp. Yangling I2, NBRC 105727, NIH 90-72, R. ornithinolytica
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