node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AJF74220.1 | apaH | TE10_20175 | TE10_06010 | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | 0.558 |
AJF74220.1 | entH | TE10_20175 | TE10_08900 | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioesterase; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | 0.568 |
AJF74220.1 | frdD | TE10_20175 | TE10_04285 | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | 0.563 |
AJF74220.1 | menA | TE10_20175 | TE10_02770 | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.542 |
AJF74220.1 | menB | TE10_20175 | TE10_20170 | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxynaphthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.949 |
AJF74220.1 | menC | TE10_20175 | TE10_20165 | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.993 |
AJF74220.1 | menD | TE10_20175 | TE10_20180 | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.999 |
AJF74220.1 | menE | TE10_20175 | TE10_20160 | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | O-succinylbenzoic acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.953 |
AJF74220.1 | menF | TE10_20175 | TE10_20185 | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.874 |
AJF74220.1 | ydiI | TE10_20175 | TE10_17265 | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioesterase; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA). | 0.652 |
apaH | AJF74220.1 | TE10_06010 | TE10_20175 | Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.558 |
entH | AJF74220.1 | TE10_08900 | TE10_20175 | Thioesterase; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.568 |
entH | menA | TE10_08900 | TE10_02770 | Thioesterase; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.697 |
entH | menB | TE10_08900 | TE10_20170 | Thioesterase; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | Dihydroxynaphthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). | 0.848 |
entH | menD | TE10_08900 | TE10_20180 | Thioesterase; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. | 0.623 |
entH | menE | TE10_08900 | TE10_20160 | Thioesterase; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | O-succinylbenzoic acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.534 |
entH | menF | TE10_08900 | TE10_20185 | Thioesterase; Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Belongs to the thioesterase PaaI family. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.499 |
frdD | AJF74220.1 | TE10_04285 | TE10_20175 | Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Catalyzes the formation of (1 R,6 R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.563 |
frdD | menA | TE10_04285 | TE10_02770 | Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.434 |
frdD | menC | TE10_04285 | TE10_20165 | Fumarate reductase; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). | 0.770 |