node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | TSAR_001635 | A0A232EJC2 | A0A232EYL2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | TSAR_004919 | A0A232EJC2 | A0A232F9X3 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | MCM domain-containing protein; Belongs to the MCM family. | 0.999 |
MCM7 | TSAR_006255 | A0A232EJC2 | A0A232F8G1 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | CDT1 domain-containing protein. | 0.999 |
MCM7 | TSAR_006454 | A0A232EJC2 | A0A232F3V3 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Protein kinase domain-containing protein. | 0.916 |
MCM7 | TSAR_007478 | A0A232EJC2 | A0A232FEX0 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | TSAR_009242 | A0A232EJC2 | A0A232F7P9 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | MCM domain-containing protein; Belongs to the MCM family. | 0.999 |
MCM7 | TSAR_010519 | A0A232EJC2 | A0A232FBN1 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.995 |
MCM7 | TSAR_010687 | A0A232EJC2 | A0A232EZJ5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase. | 0.999 |
MCM7 | TSAR_010960 | A0A232EJC2 | A0A232FCU1 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Uncharacterized protein. | 0.999 |
MCM7 | TSAR_011724 | A0A232EJC2 | A0A232FCK5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.999 |
TSAR_001635 | MCM7 | A0A232EYL2 | A0A232EJC2 | DNA helicase; Belongs to the MCM family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
TSAR_001635 | TSAR_004919 | A0A232EYL2 | A0A232F9X3 | DNA helicase; Belongs to the MCM family. | MCM domain-containing protein; Belongs to the MCM family. | 0.999 |
TSAR_001635 | TSAR_006255 | A0A232EYL2 | A0A232F8G1 | DNA helicase; Belongs to the MCM family. | CDT1 domain-containing protein. | 0.999 |
TSAR_001635 | TSAR_006454 | A0A232EYL2 | A0A232F3V3 | DNA helicase; Belongs to the MCM family. | Protein kinase domain-containing protein. | 0.916 |
TSAR_001635 | TSAR_007478 | A0A232EYL2 | A0A232FEX0 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
TSAR_001635 | TSAR_009242 | A0A232EYL2 | A0A232F7P9 | DNA helicase; Belongs to the MCM family. | MCM domain-containing protein; Belongs to the MCM family. | 0.999 |
TSAR_001635 | TSAR_010519 | A0A232EYL2 | A0A232FBN1 | DNA helicase; Belongs to the MCM family. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.995 |
TSAR_001635 | TSAR_010687 | A0A232EYL2 | A0A232EZJ5 | DNA helicase; Belongs to the MCM family. | DNA helicase. | 0.999 |
TSAR_001635 | TSAR_010960 | A0A232EYL2 | A0A232FCU1 | DNA helicase; Belongs to the MCM family. | Uncharacterized protein. | 0.996 |
TSAR_001635 | TSAR_011724 | A0A232EYL2 | A0A232FCK5 | DNA helicase; Belongs to the MCM family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.999 |