STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSAR_015750Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. (1111 aa)    
Predicted Functional Partners:
TSAR_012801
Uncharacterized protein.
   
 0.975
TSAR_005438
Uncharacterized protein.
   
 0.972
TSAR_009723
Uncharacterized protein.
   
 0.962
TSAR_014284
Uncharacterized protein.
    
 0.959
TSAR_012041
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
    
 0.958
TSAR_003313
Uncharacterized protein.
    
 0.958
TSAR_012001
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.946
TSAR_015399
HTH TFE/IIEalpha-type domain-containing protein.
   
 0.943
TSAR_010503
FHA domain-containing protein.
    
 0.943
TSAR_011964
CYCLIN domain-containing protein; Belongs to the cyclin family.
    
 0.941
Your Current Organism:
Trichomalopsis sarcophagae
NCBI taxonomy Id: 543379
Other names: T. sarcophagae
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.