close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS16685.1PFAM: Vault protein inter-alpha-trypsin domain protein; von Willebrand factor type A; SMART: von Willebrand factor type A; Vault protein inter-alpha-trypsin, metazoa; KEGG: pna:Pnap_0028 vault protein inter-alpha-trypsin subunit. (691 aa)    
Predicted Functional Partners:
ACS16682.1
PFAM: glycosyl transferase family 51; KEGG: pna:Pnap_0025 glycosyl transferase family protein.
 
    0.804
ACS16684.1
KEGG: pna:Pnap_0027 hypothetical protein.
       0.777
ACS16683.1
KEGG: pna:Pnap_0026 hypothetical protein.
       0.763
ACS16681.1
PFAM: GCN5-related N-acetyltransferase; KEGG: pol:Bpro_2418 GCN5-related N-acetyltransferase.
       0.722
ACS16680.1
PFAM: Pirin domain protein; KEGG: rso:RSc0541 pirin-like protein; Belongs to the pirin family.
       0.565
ACS16679.1
KEGG: pol:Bpro_0028 NADPH-dependent FMN reductase.
 
     0.506
ACS16686.1
PFAM: Inner membrane CreD family protein; KEGG: bcj:BCAM1996 inner membrane protein CreD.
       0.494
ACS22515.1
TIGRFAM: conserved repeat domain protein; PFAM: protein of unknown function DUF11; KEGG: pna:Pnap_0406 hypothetical protein.
 
     0.478
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
  
     0.469
ACS19420.1
Putative adenylate/guanylate cyclase; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: rfr:Rfer_2284 putative adenylate/guanylate cyclase.
 
   
 0.450
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.