close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS16763.1Fumarylacetoacetase; KEGG: bpy:Bphyt_2380 fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: Domain of unknown function DUF1969; fumarylacetoacetate (FAA) hydrolase. (441 aa)    
Predicted Functional Partners:
ACS16952.1
KEGG: pol:Bpro_2997 homogentisate 1,2-dioxygenase; TIGRFAM: homogentisate 1,2-dioxygenase; PFAM: homogentisate 12-dioxygenase.
 
  
 0.969
ACS21388.1
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: aav:Aave_0742 fumarylacetoacetate (FAA) hydrolase.
     
 0.904
ACS16950.1
Fumarylacetoacetase; KEGG: aav:Aave_0256 fumarylacetoacetate hydrolase; TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase; Domain of unknown function DUF1969.
  
  
 
0.902
ACS17017.1
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rso:RSc1086 putative isomerase-decarboxylase.
     
 0.900
ACS18663.1
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: pol:Bpro_2124 fumarylacetoacetate (FAA) hydrolase.
     
 0.900
ACS20168.1
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: pol:Bpro_1732 fumarylacetoacetate (FAA) hydrolase.
     
 0.900
ACS18664.1
KEGG: pol:Bpro_2136 maleylacetoacetate isomerase; TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase domain.
 
 0.866
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.841
ACS18079.1
TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; succinate dehydrogenase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: aav:Aave_2202 succinate dehydrogenase subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.820
ACS18078.1
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: pol:Bpro_3603 succinate dehydrogenase subunit B.
  
 
  0.809
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (38%) [HD]