close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS16764.1PFAM: cyclase family protein; KEGG: vei:Veis_0387 cyclase family protein. (268 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
  
  
 0.850
ACS16763.1
Fumarylacetoacetase; KEGG: bpy:Bphyt_2380 fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: Domain of unknown function DUF1969; fumarylacetoacetate (FAA) hydrolase.
       0.730
ACS16769.1
PFAM: regulatory protein TetR; KEGG: vei:Veis_0382 TetR family transcriptional regulator.
 
     0.695
ACS16766.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vei:Veis_0385 binding-protein-dependent transport systems inner membrane component.
       0.694
ACS16765.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vei:Veis_0386 binding-protein-dependent transport systems inner membrane component.
       0.674
ACS16767.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vei:Veis_0384 ABC transporter related.
       0.672
ACS16768.1
PFAM: NMT1/THI5 like domain protein; KEGG: vei:Veis_0383 NlpA lipoprotein.
       0.663
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
  
  
 0.543
ACS22012.1
PFAM: tryptophan 23-dioxygenase; KEGG: reu:Reut_C5980 putative tryptophan 2,3-dioxygenase.
  
  
 0.543
ACS16737.1
PFAM: protein of unknown function DUF849; KEGG: bxe:Bxe_C0921 3-keto-5-aminohexanoate cleavage enzyme.
  
    0.542
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.