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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS16957.1PFAM: Silent information regulator protein Sir2; KEGG: aeh:Mlg_2040 silent information regulator protein Sir2. (249 aa)    
Predicted Functional Partners:
ACS22848.1
TIGRFAM: cytidyltransferase-related domain protein; PFAM: NUDIX hydrolase; cytidylyltransferase; KEGG: pna:Pnap_3717 cytidyltransferase-like protein.
  
 
 0.980
nadE-2
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 0.951
nadE-3
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 0.951
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.941
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.930
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
 0.923
ACS16850.1
Nicotinamidase; PFAM: isochorismatase hydrolase; KEGG: vei:Veis_0861 nicotinamidase.
  
 0.915
ACS17054.1
NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: vei:Veis_4748 NAD(P)(+) transhydrogenase (AB-specific).
     
 0.910
ACS22611.1
NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: vei:Veis_4748 NAD(P)(+) transhydrogenase (AB-specific).
     
 0.910
ACS16815.1
PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: bpy:Bphyt_4926 inosine/uridine-preferring nucleoside hydrolase.
   
 
 0.908
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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