close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS16991.1Putative integral membrane sensor protein; PFAM: MHYT domain protein; KEGG: bbr:BB1820 hypothetical protein. (256 aa)    
Predicted Functional Partners:
ACS22670.1
KEGG: gme:Gmet_3085 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; SMART: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein.
   
 0.907
ACS22668.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: pfo:Pfl01_4551 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; response regulator receiver; PAS fold-4 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein.
 
  
 0.878
ACS18308.1
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: bph:Bphy_5975 histidine kinase.
 
    0.743
ACS16989.1
PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: rpc:RPC_3200 carbamoyl-phosphate synthase L chain, ATP-binding.
       0.570
ACS16990.1
Methylcrotonoyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: rpe:RPE_2254 propionyl-CoA carboxylase.
       0.570
ACS22172.1
KEGG: acr:Acry_0578 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; response regulator receiver; histidine kinase A domain protein; PAS domain containing protein.
 
  
 0.565
ACS20722.1
Histidine kinase; KEGG: pol:Bpro_0880 multi-sensor signal transduction histidine kinase; PFAM: CHASE3 domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
   
  
 0.545
ACS17371.1
PAS/PAC sensor hybrid histidine kinase; KEGG: scl:sce0929 two-component hybrid sensor and regulator; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
  
 0.481
ACS16992.1
PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: rpa:RPA4432 NHL repeat-containing protein.
       0.478
ACS16988.1
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: rfr:Rfer_3507 short-chain dehydrogenase/reductase SDR.
       0.477
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: medium (54%) [HD]