close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lptALipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. (239 aa)    
Predicted Functional Partners:
ACS21894.1
PFAM: protein of unknown function DUF1239; KEGG: aav:Aave_4783 hypothetical protein.
 
 
 0.989
ACS17128.1
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_4486 ABC transporter related.
  
  
 0.987
lptD
Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
 
 0.898
ACS17129.1
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.862
lptE
Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.
  
  
 0.727
ACS17588.1
PFAM: ribonuclease II; KEGG: ajs:Ajs_3654 ribonuclease II.
  
     0.726
ACS17130.1
PFAM: phospholipase D/Transphosphatidylase; SMART: phospholipase D/Transphosphatidylase; KEGG: rpi:Rpic_4172 phospholipase D/transphosphatidylase.
       0.720
ACS21761.1
KEGG: rfr:Rfer_0366 hypothetical protein.
  
   
 0.714
ACS20050.1
PFAM: NlpBDapX family lipoprotein; KEGG: rfr:Rfer_2096 NlpBDapX lipoprotein.
  
  
 0.704
ACS17126.1
PFAM: DSBA oxidoreductase; KEGG: xcv:XCV2315 putative thiol:disulfide interchange protein.
 
   
 0.702
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.