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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS17161.1TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: DNA primase small subunit; KEGG: pol:Bpro_3003 ATP-dependent DNA ligase. (298 aa)    
Predicted Functional Partners:
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.974
ACS18310.1
TIGRFAM: DNA ligase D; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; PFAM: ATP dependent DNA ligase; DNA primase small subunit; ATP dependent DNA ligase domain protein; KEGG: nmu:Nmul_A1177 ATP-dependent DNA ligase.
 
  
0.916
ACS17971.1
KEGG: aav:Aave_1492 putative DNA topoisomerase, type I.
 
     0.698
ACS20288.1
PFAM: protein of unknown function DUF72; KEGG: pfl:PFL_4743 hypothetical protein.
 
    0.696
ACS21885.1
PFAM: protein of unknown function DUF72; KEGG: pol:Bpro_4869 protein of unknown function DUF72.
 
    0.679
ACS21463.1
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: aav:Aave_0375 ATP-dependent DNA ligase.
 
   
 0.569
ACS17159.1
PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: bbr:BB2668 putative succinylglutamate desuccinylase.
       0.551
ACS18630.1
KEGG: rfr:Rfer_2156 malto-oligosyltrehalose synthase; TIGRFAM: malto-oligosyltrehalose synthase; 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain.
 
    0.428
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.411
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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