Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACS17459.1KEGG: vei:Veis_1916 isocitrate lyase family protein. (287 aa)    
Predicted Functional Partners:
ACS17458.1
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: vei:Veis_1915 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein.
 
  
 0.924
ACS17453.1
KEGG: met:M446_1932 MmgE/PrpD family protein.
 
  
 0.894
ACS17457.1
PFAM: isochorismatase hydrolase; KEGG: vei:Veis_1914 isochorismatase hydrolase.
 
    0.883
ACS17455.1
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase B/oxoprolinase; KEGG: vei:Veis_1912 5-oxoprolinase (ATP-hydrolyzing).
 
     0.838
ACS17456.1
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: vei:Veis_1913 5-oxoprolinase (ATP-hydrolyzing).
 
     0.819
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.802
ACS17454.1
PFAM: conserved hypothetical protein; KEGG: reu:Reut_B3664 hypothetical protein.
       0.775
ACS20923.1
PFAM: protein of unknown function DUF453; KEGG: rsk:RSKD131_4240 methylitaconate delta2-delta3-isomerase.
 
  
 0.753
ACS22245.1
KEGG: bpt:Bpet2878 citrate synthase.
 
 
 0.745
ACS22711.1
PFAM: MmgE/PrpD family protein; KEGG: dac:Daci_1760 MmgE/PrpD family protein.
 
  
 0.736
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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