node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS17551.1 | dapF | Vapar_0900 | Vapar_0899 | PFAM: protein of unknown function DUF484; KEGG: rfr:Rfer_3443 hypothetical protein. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.978 |
ACS17551.1 | xerC | Vapar_0900 | Vapar_0902 | PFAM: protein of unknown function DUF484; KEGG: rfr:Rfer_3443 hypothetical protein. | Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.902 |
ACS20543.1 | ACS22198.1 | Vapar_3929 | Vapar_5606 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: pol:Bpro_1422 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: vei:Veis_0720 peptidase M20. | 0.903 |
ACS20543.1 | dapE | Vapar_3929 | Vapar_2717 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: pol:Bpro_1422 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.919 |
ACS20543.1 | dapF | Vapar_3929 | Vapar_0899 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: pol:Bpro_1422 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.909 |
ACS22198.1 | ACS20543.1 | Vapar_5606 | Vapar_3929 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: vei:Veis_0720 peptidase M20. | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: pol:Bpro_1422 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | 0.903 |
ACS22198.1 | dapE | Vapar_5606 | Vapar_2717 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: vei:Veis_0720 peptidase M20. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.919 |
ACS22198.1 | dapF | Vapar_5606 | Vapar_0899 | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: vei:Veis_0720 peptidase M20. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.909 |
asd | dapF | Vapar_1419 | Vapar_0899 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.900 |
asd | lysA | Vapar_1419 | Vapar_1136 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.522 |
carB | dapF | Vapar_2617 | Vapar_0899 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: pol:Bpro_2678 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.861 |
carB | lysA | Vapar_2617 | Vapar_1136 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: pol:Bpro_2678 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.439 |
dapE | ACS20543.1 | Vapar_2717 | Vapar_3929 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: pol:Bpro_1422 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | 0.919 |
dapE | ACS22198.1 | Vapar_2717 | Vapar_5606 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: vei:Veis_0720 peptidase M20. | 0.919 |
dapE | dapF | Vapar_2717 | Vapar_0899 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.918 |
dapE | rppH | Vapar_2717 | Vapar_4213 | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.559 |
dapF | ACS17551.1 | Vapar_0899 | Vapar_0900 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | PFAM: protein of unknown function DUF484; KEGG: rfr:Rfer_3443 hypothetical protein. | 0.978 |
dapF | ACS20543.1 | Vapar_0899 | Vapar_3929 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: pol:Bpro_1422 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. | 0.909 |
dapF | ACS22198.1 | Vapar_0899 | Vapar_5606 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: vei:Veis_0720 peptidase M20. | 0.909 |
dapF | asd | Vapar_0899 | Vapar_1419 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.900 |