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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS17678.1KEGG: rso:RSp0996 tartrate dehydrogenase oxidoreductase protein; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase. (354 aa)    
Predicted Functional Partners:
ACS18996.1
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: vei:Veis_1746 acetolactate synthase 3 regulatory subunit.
  
 0.912
ACS22205.1
PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: vei:Veis_2510 Fe-S type hydro-lyases tartrate/fumarate beta region.
  
 
 0.912
ACS22073.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: rfr:Rfer_2799 pyruvate flavodoxin/ferredoxin oxidoreductase-like.
     
 0.908
ACS22206.1
KEGG: vei:Veis_2511 tartrate/fumarate subfamily Fe-S type hydro-lyase alpha subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region.
    
 0.907
ACS18438.1
KEGG: pol:Bpro_3066 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase.
  
  
 
0.906
ACS22230.1
KEGG: aav:Aave_2191 tartrate dehydrogenase; TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase.
  
  
 
0.906
ACS22072.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: rfr:Rfer_2798 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
   
 
 0.904
ACS17451.1
TIGRFAM: homoaconitate hydratase family protein; PFAM: aconitate hydratase domain protein; KEGG: vei:Veis_1910 3-isopropylmalate dehydratase large subunit.
 
 0.878
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 0.816
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.794
Your Current Organism:
Variovorax paradoxus S110
NCBI taxonomy Id: 543728
Other names: V. paradoxus S110, Variovorax paradoxus str. S110, Variovorax paradoxus strain S110
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