node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS17813.1 | ACS19848.1 | Vapar_1162 | Vapar_3230 | PFAM: BolA family protein; KEGG: aav:Aave_1021 BolA family protein; Belongs to the BolA/IbaG family. | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bbr:BB1554 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | 0.489 |
ACS17813.1 | hisD | Vapar_1162 | Vapar_1165 | PFAM: BolA family protein; KEGG: aav:Aave_1021 BolA family protein; Belongs to the BolA/IbaG family. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.736 |
ACS17813.1 | hisG | Vapar_1162 | Vapar_1164 | PFAM: BolA family protein; KEGG: aav:Aave_1021 BolA family protein; Belongs to the BolA/IbaG family. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.818 |
ACS17813.1 | murA | Vapar_1162 | Vapar_1163 | PFAM: BolA family protein; KEGG: aav:Aave_1021 BolA family protein; Belongs to the BolA/IbaG family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.813 |
ACS18573.1 | ACS19848.1 | Vapar_1926 | Vapar_3230 | TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: ajs:Ajs_3014 UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bbr:BB1554 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | 0.906 |
ACS18573.1 | glmU | Vapar_1926 | Vapar_0999 | TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: ajs:Ajs_3014 UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.932 |
ACS18573.1 | lpxA | Vapar_1926 | Vapar_2611 | TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: ajs:Ajs_3014 UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.841 |
ACS18573.1 | murA | Vapar_1926 | Vapar_1163 | TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: ajs:Ajs_3014 UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.906 |
ACS19848.1 | ACS17813.1 | Vapar_3230 | Vapar_1162 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bbr:BB1554 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | PFAM: BolA family protein; KEGG: aav:Aave_1021 BolA family protein; Belongs to the BolA/IbaG family. | 0.489 |
ACS19848.1 | ACS18573.1 | Vapar_3230 | Vapar_1926 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bbr:BB1554 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: ajs:Ajs_3014 UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.906 |
ACS19848.1 | ACS21863.1 | Vapar_3230 | Vapar_5261 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bbr:BB1554 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | PFAM: Nucleotidyl transferase; KEGG: pna:Pnap_4057 nucleotidyl transferase. | 0.815 |
ACS19848.1 | glmU | Vapar_3230 | Vapar_0999 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bbr:BB1554 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.925 |
ACS19848.1 | lpxA | Vapar_3230 | Vapar_2611 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bbr:BB1554 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.879 |
ACS19848.1 | murA | Vapar_3230 | Vapar_1163 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bbr:BB1554 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.913 |
ACS19848.1 | murB | Vapar_3230 | Vapar_3768 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bbr:BB1554 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.940 |
ACS19848.1 | murC | Vapar_3230 | Vapar_0920 | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bbr:BB1554 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.565 |
ACS21863.1 | ACS19848.1 | Vapar_5261 | Vapar_3230 | PFAM: Nucleotidyl transferase; KEGG: pna:Pnap_4057 nucleotidyl transferase. | PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); KEGG: bbr:BB1554 putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase. | 0.815 |
ACS21863.1 | murA | Vapar_5261 | Vapar_1163 | PFAM: Nucleotidyl transferase; KEGG: pna:Pnap_4057 nucleotidyl transferase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.815 |
ACS21863.1 | murB | Vapar_5261 | Vapar_3768 | PFAM: Nucleotidyl transferase; KEGG: pna:Pnap_4057 nucleotidyl transferase. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.904 |
ACS21863.1 | murC | Vapar_5261 | Vapar_0920 | PFAM: Nucleotidyl transferase; KEGG: pna:Pnap_4057 nucleotidyl transferase. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.814 |